A major metabolite of eplerenone
Related Products
Parent Compound(s)
15616Eplerenone
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6β-hydroxy Eplerenone

Item No. 28859

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(6β,7α,11α,17α)-9,11-epoxy-6,17-dihydroxy-3-oxo-pregn-4-ene-7,21-dicarboxylic acid, γ-lactone, methyl ester
CAS Number
209253-80-5
Molecular Formula
C24H30O7
Formula Weight
430.5
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Methanol: soluble
SMILES
O=C1CC[C@@]2(C)C([C@H](O)[C@@H](C(OC)=O)[C@]3([H])[C@]2(O4)[C@H]4C[C@@]5(C)[C@@]3([H])CC[C@]56OC(CC6)=O)=C1
InChi Code
InChI=1S/C24H30O7/c1-21-7-4-12(25)10-14(21)19(27)17(20(28)29-3)18-13-5-8-23(9-6-16(26)31-23)22(13,2)11-15-24(18,21)30-15/h10,13,15,17-19,27H,4-9,11H2,1-3H3/t13-,15+,17-,18+,19-,21-,22-,23+,24+/m0/s1
InChi Key
DDHQRXOAZNEFKY-LRKJUHPMSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    1 mg

    $493

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    Product Description

    6β-hydroxy Eplerenone is a major metabolite of the mineralocorticoid receptor antagonist eplerenone (Item No. 15616).1 It is formed from eplerenone by the cytochrome P450 (CYP) isoform CYP3A4.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Cook, C.S., Berry, L.M., Kim, D.H., et al. Involvement of CYP3A in the metabolism of eplerenone in humans and dogs: Differential metabolism by CYP3A4 and CYP3A5. Drug Metab. Dispos. 30(12), 1344-1351 (2002).