An Analytical Reference Standard
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Exempt Preparation(s)
34023(−)-11-hydroxy-Δ8-THC (CRM)
Isomer(s)
36517(–)-7-hydroxy Cannabidiol 33076(–)-7-hydroxy Cannabidiol (CRM) 21667(±)-11-hydroxy-Δ9-THC (CRM) 41185(±)-11-hydroxy-Δ9-THC (CRM) 40854(±)-6',7'-epoxy Cannabichromene 40853(±)-8'-hydroxy Cannabichromene 14239(−)-11-hydroxy-Δ9-THC 27576(−)-6α-hydroxy Cannabidiol 38231(6aR,9R)-11-hydroxy-Δ10-THC 41299(6aR,9R)-11-hydroxy-Δ10-THC (exempt preparation) 3802010α-hydroxy-exo-THC 3802210α-hydroxy-Δ8-THC 275776β-hydroxy Cannabidiol 377658α-hydroxy-exo-THC 376348α-hydroxy-Δ9-THC 397938α-hydroxy-Δ9-THC (exempt preparation) 420218α,9α-epoxy Hexahydrocannabinol 446098α,9α-epoxy Hexahydrocannabinol (exempt preparation) 446938α,9α-epoxy Hexahydrocannabinol (exempt preparation) 377668β-hydroxy-exo-THC 397968β-hydroxy-exo-THC (exempt preparation) 376358β-hydroxy-Δ9-THC 397948β-hydroxy-Δ9-THC (exempt preparation) 420228β,9β-epoxy Hexahydrocannabinol 446088β,9β-epoxy Hexahydrocannabinol (exempt preparation) 446948β,9β-epoxy Hexahydrocannabinol (exempt preparation) 399729α,10α-epoxy Hexahydrocannabinol 446109α,10α-epoxy Hexahydrocannabinol (exempt preparation) 446929α,10α-epoxy Hexahydrocannabinol (exempt preparation) 420239β,10β-epoxy Hexahydrocannabinol 446079β,10β-epoxy Hexahydrocannabinol (exempt preparation) 446959β,10β-epoxy Hexahydrocannabinol (exempt preparation) 21092Cannabielsoin 36661Cannabielsoin (CRM) 36829Hexocannabitriol
Labeled Version(s)
37040(−)-11-hydroxy-Δ8-THC-d3 40976(−)-11-hydroxy-Δ8-THC-d3 (exempt preparation)
Parent Compound(s)
35329(+)-Δ8-THC 14042Δ8-THC 41193Δ8-THC (Alt. Batch CRM) ISO60158Δ8-THC (CRM)
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(−)-11-hydroxy-Δ8-THC

Item No. 29469

Restricted Product (Schedule I)
Product Insert (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • (−)-11-hydroxy-Δ8-Tetrahydrocannabinol
  • (–)-trans-Δ8-THC
  • 7-hydroxy-Δ6-THC
Technical Information
Formal Name
(6aR,10aR)-6a,7,10,10a-tetrahydro-1-hydroxy-6,6-dimethyl-3-pentyl-6H-dibenzo[b,d]pyran-9-methanol
CAS Number
28646-40-4
Molecular Formula
C21H30O3
Formula Weight
330.5
Purity
≥98%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 60 mg/mlDMF:PBS (pH 7.2) (1:3): 0.25 mg/mlDMSO: 50 mg/mlEthanol: 25 mg/mlMethanol: 30 mg/ml
SMILES
[H][C@]12C3=C(C=C(CCCCC)C=C3O)OC(C)(C)[C@]1([H])CC=C(CO)C2
InChi Code
InChI=1S/C21H30O3/c1-4-5-6-7-14-11-18(23)20-16-10-15(13-22)8-9-17(16)21(2,3)24-19(20)12-14/h8,11-12,16-17,22-23H,4-7,9-10,13H2,1-3H3/t16-,17-/m1/s1
InChi Key
LOUSQMWLMDHRIK-IAGOWNOFSA-N
Regulatory Information
DEA Schedule
I
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Certificates of Analysis & Batch Specific Data

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    1 mg

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    Product Description

    (−)-11-hydroxy-Δ8-THC (Item No. 29469) is an analytical reference standard categorized as a phytocannabinoid metabolite.1,2 (–)-11-hydroxy-Δ8-THC is a metabolite of Δ8-THC (Item Nos. ISO60158 | 14042). It has analgesic activity in mice. (–)-11-hydroxy-Δ8-THC is regulated as a Schedule I compound in the United States. This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Watanabe, K., Yamamoto, I., Oguri, K., et al. Comparison in mice of pharmacological effects of Δ8-tetrahydrocannabinol and its metabolites oxidized at 11-position. Eur. J. Pharm. 63(1), 1-6 (1980).

    2. Rhee, M.H., Vogel, Z., Barg, J., et al. Cannabinol derivatives: Binding to cannabinoid receptors and inhibition of adenylylcyclase. J. Med. Chem. 40(20), 3228-3233 (1997).

    Product Citations

    Schirmer, W., Walton, S.E., Weinmann, W., et al. Rapid LC-QTOF-MS screening method for semi-synthetic cannabinoids in whole blood. J. Anal. Toxicol. bkaf095 (2025).