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(−)-11-hydroxy-Δ8-THC-d3

Item No. 37040

Synonyms
Synonyms
  • (−)-11-hydroxy-Δ8-Tetrahydrocannabinol-d3
  • (−)-trans8-THC-d3
  • 7-hydroxy-Δ6-THC-d3
Technical Information
Formal Name
(6aR,10aR)-9-(hydroxymethyl)-6,6-dimethyl-3-(pentyl-5,5,5-d3)-6a,7,10,10a-tetrahydro-6H-benzo[c]chromen-1-ol
Molecular Formula
C21H27D3O3
Formula Weight
Purity
≥99% deuterated forms (d1-d3)
Formulation
A crystalline solid
DMF: 60 mg/mlDMF:PBS (pH 7.2) (1:3): 0.25 mg/mlDMSO: 50 mg/mlEthanol: 25 mg/mlMethanol: 30 mg/ml
SMILES
[H][C@]12C3=C(C=C(CCCCC([2H])([2H])[2H])C=C3O)OC(C)(C)[C@]1([H])CC=C(CO)C2
InChi Code
InChI=1S/C21H30O3/c1-4-5-6-7-14-11-18(23)20-16-10-15(13-22)8-9-17(16)21(2,3)24-19(20)12-14/h8,11-12,16-17,22-23H,4-7,9-10,13H2,1-3H3/t16-,17-/m1/s1/i1D3
InChi Key
LOUSQMWLMDHRIK-MVOYJBSWSA-N
Regulatory Information
DEA Schedule
I
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    Product Description

    (−)-11-hydroxy-Δ8-THC-d3 (Item No. 37040) is intended for use as an internal standard for the quantification of (−)-11-hydroxy-Δ8-THC (Item No. 29469) by GC- or LC-MS. (−)-11-hydroxy-Δ8-THC is categorized as a phytocannabinoid metabolite.1,2 (–)-11-hydroxy-Δ8-THC is a metabolite of Δ8-THC (Item Nos. ISO60158 | 14042). It has analgesic activity in mice. (–)-11-hydroxy-Δ8-THC-d3 is regulated as a Schedule I compound in the United States. This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Watanabe, K., Yamamoto, I., Oguri, K., et alComparison in mice of pharmacological effects of Δ8-tetrahydrocannabinol and its metabolites oxidized at 11-position. Eur. J. Pharm. 63(1), 1-6 (1980).

    2. Rhee, M.H., Vogel, Z., Barg, J., et alCannabinol derivatives: Binding to cannabinoid receptors and inhibition of adenylylcyclase. J. Med. Chem. 40(20), 3228-3233 (1997).