A monosaccharide
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1,5-Anhydro-D-glucitol

Item No. 29874

Technical Information
CAS Number
154-58-5
Synonyms
  • 1,5-AG
  • 1,5-Anhydroglucitol
  • 1,5-Anhydro-D-sorbitol
  • 1,5-Anhydrosorbitol
  • 1-Deoxy-D-glucopyranose
  • 1-Deoxy-D-glucose
  • 1,5-D-Sorbitol
Molecular Formula
C6H12O5
Formula Weight
Purity
≥95%
A crystalline solid
DMF: 30 mg/mlDMSO: 25 mg/mlEthanol: 2 mg/mlPBS (pH 7.2): 10 mg/ml
SMILES
OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)CO1
InChi Code
InChI=1S/C6H12O5/c7-1-4-6(10)5(9)3(8)2-11-4/h3-10H,1-2H2/t3-,4+,5+,6+/m0/s1
InChi Key
MPCAJMNYNOGXPB-SLPGGIOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    1,5-Anhydro-D-glucitol (1,5-AG) is a monosaccharide and a metabolically inert analog of D-glucose that has been found in a variety of dietary sources including soy, white rice, pasta, vegetables, fish, and tea.1,2 Renal reabsorption of 1,5-AG is blocked by glucose, and serum levels of 1,5-AG are decreased by repeated episodes of hypoglycemia. Serum levels of 1,5-AG have been used as a supplementary glycemic marker to hemoglobin A1c (HbA1c) levels in patients with diabetes mellitus.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Dungan, K.M. 1,5-anhydroglucitol (GlycoMark) as a marker of short-term glycemic control and glycemic excursions. Expert Rev. Mol. Diagn. 8(1), 9-19 (2008).

    2. Kim, W.J., and Park, C.Y. 1,5-Anhydroglucitol in diabetes mellitus. Endrocrine 43(1), 33-40 (2013).