An internal standard for the quantification of D-fructose
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D-Fructose-13C6

Item No. 30071

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
D-fructose-1,2,3,4,5,6-13C6
CAS Number
201595-65-5
Synonyms
  • D-(–)-Fructose-13C6
  • D-(–)-Levulose-13C6
Molecular Formula
[13C]6H12O6
Formula Weight
186.1
Purity
≥95%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMSO: 1 mg/mlPBS (pH 7.2): 10 mg/ml
SMILES
O[13CH2][13C@@H](O)[13C@@H](O)[13C@H](O)[13C]([13CH2]O)=O
InChi Code
InChI=1S/C6H12O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3,5-9,11-12H,1-2H2/t3-,5-,6-/m1/s1/i1+1,2+1,3+1,4+1,5+1,6+1
InChi Key
BJHIKXHVCXFQLS-HJLYHLTLSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    100 mg

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    OBESITY RESEARCH SOLUTIONS
    Product Description

    D-Fructose-13C6 is intended for use as an internal standard for the quantification of D-fructose by GC- or LC-MS. D-Fructose is a ubiquitous monosaccharide and is derived, in addition to glucose, from the breakdown of sucrose by sucrase in the intestine.1 It is a precursor in the biosynthesis of D-fructose-1,6-bisphosphate (Item No. 20516), which is an intermediate in the production of D-glucose via gluconeogenesis. Deficiencies in the enzymes that metabolize D-fructose are inborn errors of metabolism that range from benign, for fructokinase deficiency, to severe, for hereditary fructose intolerance, if D-fructose, sucrose, and sorbitol are not eliminated from the diet.2 Increased consumption of D-fructose is associated with obesity, dyslipidemia, and impaired insulin sensitivity.3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Chen, M., and Whistler, R.L. Metabolism of D-fructose. Adv. Carbohydr. Chem. Biochem. 34, 265-343 (1977).

    2. Tran, C. Inborn errors of fructose metabolism. What can we learn from them? Nutrients 9(4), E356 (2017).

    3. Tappy, L., and Lě, K.-A. Metabolic effects of fructose and the worldwide increase in obesity. Physiol. Rev. 90(1), 23-46 (2010).