A ginsenoside with diverse biological activities
Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

Pseudoginsenoside F11

Item No. 30222

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(3β,6α,12β,24R)-20,24-epoxy-3,12,25-trihydroxydammaran-6-yl 2-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranoside
CAS Number
69884-00-0
Synonyms
  • Ginsenoside A1
Molecular Formula
C42H72O14
Formula Weight
801.0
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMF: 15 mg/mlDMSO: 10 mg/mlEthanol: 0.1 mg/mlPBS (pH 7.2): 1 mg/ml
SMILES
CC(C)(O)[C@H](O1)CC[C@@]1(C)[C@@]2([H])CC[C@@]3(C)[C@]4(C)C[C@H](O[C@H]5[C@H](O[C@H]6[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O6)[C@@H](O)[C@H](O)[C@@H](CO)O5)[C@@]7([H])C(C)(C)[C@@H](O)CC[C@]7(C)[C@@]4([H])C[C@@H](O)[C@@]32[H]
InChi Code
InChI=1S/C42H72O14/c1-19-28(46)30(48)32(50)35(52-19)55-33-31(49)29(47)23(18-43)54-36(33)53-22-17-41(8)24(39(6)13-11-25(45)37(2,3)34(22)39)16-21(44)27-20(10-14-40(27,41)7)42(9)15-12-26(56-42)38(4,5)51/h19-36,43-51H,10-18H2,1-9H3/t19-,20-,21+,22-,23+,24+,25-,26+,27-,28-,29+,30+,31-,32+,33+,34-,35-,36+,39+,40+,41+,42-/m0/s1
InChi Key
JBGYSAVRIDZNKA-NKECSCAMSA-N
Origin
Plant/Panax ginseng
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    25 mg

    $183

    Add

    50 mg

    $345

    Add

    100 mg

    $505

    Add

    250 mg

    $902

    Add
    Product Description

    Pseudoginsenoside F11 is an ocotillol-type ginsenoside that has been found in P. ginseng and has diverse biological activities.1,2,3,4 In vivo, pseudoginsenoside F11 (10 mg/kg) prevents tubular cell apoptosis, decreases in renal glutathione peroxidase (GPX) and superoxide dismutase (SOD) levels, and increases in renal lipid peroxide levels in a rat model of nephrotoxicity induced by cisplatin (Item No. 13119).1 It reduces infarct size, brain water content, and cortical accumulation of autophagosomes in a rat model of ischemic stroke induced by permanent middle cerebral artery occlusion.2 Pseudoginsenoside F11 (4 and 8 mg/kg) inhibits morphine-induced memory impairment in the Morris water maze and development of morphine-induced conditioned place preference in mice.3 It also reduces hippocampal advanced glycation end product (AGE) and malondialdehyde (MDA) levels, increases hippocampal SOD activity and glutathione (GSH) levels, and attenuates cognitive impairment in the Morris water maze in a mouse model of D-galactose-induced mild cognitive impairment.4

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Wang, H., Kong, L., Zhang, J., et al. The pseudoginsenoside F11 ameliorates cisplatin-induced nephrotoxicity without compromising its anti-tumor activity in vivo. Sci. Rep. 4, 4986 (2014).

    2. Liu, Y.Y., Zhang, T.Y., Xue, X., et al. Pseudoginsenoside-F11 attenuates cerebral ischemic injury by alleviating autophagic/lysosomal defects. CNS Neurosci. Ther. 23(7), 567-579 (2017).

    3. Li, Z., Wu, C.F., Pei, G., et al. Antagonistic effect of pseudoginsenoside-F11 on the behavioral actions of morphine in mice. Pharmacol. Biochem. Behav. 66(3), 595-601 (2000).

    4. Zhang, Z., Yang, H., Yang, J., et al. Pseudoginsenoside-F11 attenuates cognitive impairment by ameliorating oxidative stress and neuroinflammation in ᴅ‑galactose-treated mice. Int. Immunopharmacol. 67, 78-86 (2019).