An anticonvulsant
Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

Product Categories

Product Type

Biochemicals

Research Area

Neuroscience
Seizure Disorders

Valrocemide

Item No. 30909

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-(2-amino-2-oxoethyl)-2-propyl-pentanamide
CAS Number
92262-58-3
Synonyms
  • N-Valproyl glycinamide
  • TV1901
  • VGD
Molecular Formula
C10H20N2O2
Formula Weight
200.3
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMF: 30mg/mLDMSO: 30mg/mLDMSO:PBS (pH 7.2) (1:4): 0.2mg/mLEthanol: 25mg/mL
SMILES
CCCC(CCC)C(NCC(N)=O)=O
InChi Code
InChI=1S/C10H20N2O2/c1-3-5-8(6-4-2)10(14)12-7-9(11)13/h8H,3-7H2,1-2H3,(H2,11,13)(H,12,14)
InChi Key
RALGCAOVRLYSMA-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    50 mg

    $69

    Add

    100 mg

    $106

    Add

    250 mg

    $183

    Add
    Product Description

    Valrocemide is an anticonvulsant and a derivative of valproic acid (Item No. 13033).1 In vivo, valrocemide protects against seizures induced by maximal electroshock (MES), pentylenetetrazole (PTZ; Item No. 18682), picrotoxin (Item No. 20771), or bicuculline (Item No. 11727) in mice (ED50s = 151, 132, 275, and 248 mg/kg, respectively). It prevents sound-induced seizures in Frings audiogenic-sensitive mice (ED50 = 52 mg/kg) and MES-induced seizures in rats (ED50 = 73 mg/kg). Valrocemide also prevents seizures in corneally kindled rats (ED50 = 161 mg/kg).

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Isoherranen, N., Woodhead, J.H., White, H.S., et al. Anticonvulsant profile of valrocemide (TV1901): A new antiepileptic drug. Epilepsia 42(7), 831-836 (2001).