A monoterpenoid with diverse biological activities
Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

Safranal

Item No. 31399

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2,6,6-trimethyl-1,3-cyclohexadiene-1-carboxaldehyde
CAS Number
116-26-7
Molecular Formula
C10H14O
Formula Weight
150.2
Purity
≥98%
Formulation (Request formulation change)
A neat oil
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMSO: 30 mg/ml
λmax
230, 310 nm
SMILES
O=CC1=C(C)C=CCC1(C)C
InChi Code
InChI=1S/C10H14O/c1-8-5-4-6-10(2,3)9(8)7-11/h4-5,7H,6H2,1-3H3
InChi Key
SGAWOGXMMPSZPB-UHFFFAOYSA-N
Origin
Synthetic
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    1 g

    $36

    Add

    5 g

    $128

    Add

    10 g

    $219

    Add

    25 g

    $420

    Add
    Lipid Resource Center
    Discover Products & Resources for Lipid Research
    • High-purity lipid standards
    • Lipid roles in biology
    • Lipids in health & disease
    • Lipids for pharmaceutical development
    • Protocols, advice, & resources
    EXPLORE NOW
    Product Description

    Safranal is a monoterpenoid that has been found in C. sativus and has diverse biological activities, including microtubule polymerization inhibitory, cancer cell growth inhibitory, and antioxidant properties.1,2,3,4 It decreases microtubule polymerization in a cell-free assay (IC50 = 72.19 µM) and inhibits the growth of HeLa cells (IC50 = 95 µM).1,2 Safranal (145.5, 363.75, and 727.5 mg/kg) reduces the levels of thiobarbituric acid reactive substances (TBARS) and malondialdehyde (MDA) in the hippocampus in a rat model of global cerebral ischemia.3 It also reduces convulsions induced by pentylenetetrazole (Item No. 18682) in mice.4

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Naghshineh, A., Dadras, A., Ghalandari, B., et al. Safranal as a novel anti-tubulin binding agent with potential use in cancer therapy: An in vitro study. Chem. Biol. Interact. 238, 151-160 (2015).

    2. Cheriyamundath, S., Choudhary, S., and Lopus, M. Safranal inhibits HeLa cell viability by perturbing the reassembly potential of microtubules. Phytother. Res. 32(1), 170-173 (2018).

    3. Hosseinzadeh, H., and Sadeghnia, H.R. Safranal, a constituent of Crocus sativus (saffron), attenuated cerebral ischemia induced oxidative damage in rat hippocampus. J. Pharm. Pharm. Sci. 8(3), 394-399 (2005).

    4. Hosseinzadeh, H., and Talebzadeh, F. Anticonvulsant evaluation of safranal and crocin from Crocus sativus in mice. Fitoterapia 76(7-8), 722-724 (2005).