A β-AR antagonist
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Nifenalol (hydrochloride)

Item No. 32944

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
α-[[(1-methylethyl)amino]methyl]-4-nitro-benzenemethanol, monohydrochloride
CAS Number
5704-60-9
Synonyms
  • INPEA
Molecular Formula
C11H16N2O3 • HCl
Formula Weight
260.7
Purity
≥95%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMSO: 30 mg/mlEthanol: 5 mg/mlPBS (pH 7.2): 10 mg/ml
λmax
265 nm
SMILES
OC(CNC(C)C)C(C=C1)=CC=C1[N+]([O-])=O.Cl
InChi Code
InChI=1S/C11H16N2O3.ClH/c1-8(2)12-7-11(14)9-3-5-10(6-4-9)13(15)16;/h3-6,8,11-12,14H,7H2,1-2H3;1H
InChi Key
STGOXRVTUNXXLQ-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    5 mg

    $41

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    10 mg

    $72

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    25 mg

    $157

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    50 mg

    $235

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    Product Description

    Nefenalol is an antagonist of β-adrenergic receptors (β-ARs).1 It inhibits contractions induced by the β-AR agonist isoprenaline (isoproterenol; Item No. 15592) in isolated rabbit right ventricular strips (pA2 = 6.05).

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Singh, B.N., and Williams, E.M. Effects on cardiac muscle of the β-adrenoceptor blocking drugs INPEA and LB46 in relation to their local anaesthetic action on nerve. Br. J. Pharmacol. 43(1), 10-22 (1971).