An isomer of hydroxychloroquine
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Product Categories

Product Type

Biochemicals

Research Area

Endocrinology & Metabolism
Metabolic Diseases
Diabetes

(R)-Hydroxychloroquine (sulfate)

Item No. 33442

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2-[[(4R)-4-[(7-chloro-4-quinolinyl)amino]pentyl]ethylamino]-ethanol, monosulfate
CAS Number
2488706-20-1
Synonyms
  • (R)-HCQ
Molecular Formula
C18H26ClN3O • H2SO4
Formula Weight
434.0
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: solubleMethanol: solubleWater: soluble
SMILES
OCCN(CC)CCC[C@@H](C)NC1=CC=NC2=C1C=CC(Cl)=C2.O=S(O)(O)=O
InChi Code
InChI=1S/C18H26ClN3O.H2O4S/c1-3-22(11-12-23)10-4-5-14(2)21-17-8-9-20-18-13-15(19)6-7-16(17)18;1-5(2,3)4/h6-9,13-14,23H,3-5,10-12H2,1-2H3,(H,20,21);(H2,1,2,3,4)/t14-;/m1./s1
InChi Key
JCBIVZZPXRZKTI-PFEQFJNWSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    500 µg

    $81

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    1 mg

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    Cayman Chemical
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    OBESITY RESEARCH SOLUTIONS
    Product Description

    (R)-Hydroxychloroquine is an isomer of hydroxychloroquine (Item No. 17911).1 (R)-Hydroxychloroquine (2.5-20 mg/ml) reduces the rate of insulin degradation in isolated liver homogenates from non-diabetic and diabetic rats. Formulations containing hydroxychloroquine have been used in the prevention or treatment of malaria, as well as in the treatment of rheumatoid arthritis and systemic lupus erythematosus.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Emami, J., Pasutto, F.M., Mercer, J.R., et al. Inhibition of insulin metabolism by hydroxychloroquine and its enantiomers in cytosolic fraction of liver homogenates from healthy and diabetic rats. Life Sci. 64(5), 325-335 (1999).