A ribonucleoside
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Isomer(s)
34373Inosine 16492Isoprinosine
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Allopurinol Riboside

Item No. 33459

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
1,5-dihydro-1-β-D-ribofuranosyl-4H-pyrazolo[3,4-d]pyrimidin-4-one
CAS Number
16220-07-8
Synonyms
  • Allopurinol Ribonucleoside
  • NSC 138437
  • NSC 252629
Molecular Formula
C10H12N4O5
Formula Weight
268.2
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: 5 mg/mlPBS (pH 7.2): 5 mg/ml
SMILES
O=C(N=CN1)C2=C1N([C@@]3([H])[C@H](O)[C@H](O)[C@@H](CO)O3)N=C2
InChi Code
InChI=1S/C10H12N4O5/c15-2-5-6(16)7(17)10(19-5)14-8-4(1-13-14)9(18)12-3-11-8/h1,3,5-7,10,15-17H,2H2,(H,11,12,18)/t5-,6-,7-,10-/m1/s1
InChi Key
KFQUAMTWOJHPEJ-DAGMQNCNSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    5 mg

    $52

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    10 mg

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    25 mg

    $201

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    Cayman Chemical
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    Product Description

    Allopurinol riboside is a ribonucleoside and a ribose-containing derivative of the xanthine oxidase inhibitor allopurinol (Item No. 10012597).1 It inhibits the growth of Leishmania promastigotes and prevents amastigote maturation into the promastigote phase of the parasite life cycle in cell-free assays.2 Allopurinol riboside (239, 511, and 929 mg/kg per day) prevents mortality in mouse models of T. cruzi infection but does not eradicate the infection.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Croft, S.L., and Neal, R.A. The effect of allopurinol ribonucleoside and formycin B on Trypanosoma cruzi infections in mice. Trans. R. Soc. Trop. Med. Hyg. 79(4), 517-518 (1985).

    2. Nelson, D.J., LaFon, S.W., Tuttle, J.V., et al. Allopurinol ribonucleoside as an antileishmanial agent. Biological effects, metabolism, and enzymatic phosphorylation. 254(22), 11544-11549 (1979).