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17-Epiestriol is a metabolite of estrone (Item No. 10006485).1 It is formed from estrone via a 16α-hydroxy estrone (Item No. 15208) intermediate by reduction of the C-17 ketone. 17-Epiestriol binds to estrogen receptor α (ERα) and ERβ with relative binding affinities of 29 and 80 compared with 17β-estradiol (Item No. 10006315).
WARNING This product is not for human or veterinary use.
1. Serum estrogens and estrogen metabolites and endometrial cancer risk among postmenopausal women. Cancer Epidemiol. Biomarkers Prev. 25(7), 1081-1089 (2016).