An inactive metabolite of cyclophosphamide
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Parent Compound(s)
13849Cyclophosphamide (hydrate)
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4-oxo Cyclophosphamide

Item No. 33976

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2-[bis(2-chloroethyl)amino]tetrahydro-4H-1,3,2-oxazaphosphorin-4-one, 2-oxide
CAS Number
27046-19-1
Synonyms
  • 4-keto CP
  • 4-keto Cyclophosphamide
  • NSC 139488
  • 4-oxo CP
Molecular Formula
C7H13Cl2N2O3P
Formula Weight
275.1
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: Slightly solubleMethanol: Slightly soluble
SMILES
O=C1NP(OCC1)(N(CCCl)CCCl)=O
InChi Code
InChI=1S/C7H13Cl2N2O3P/c8-2-4-11(5-3-9)15(13)10-7(12)1-6-14-15/h1-6H2,(H,10,12,13)
InChi Key
VBMZHOCORXMDJU-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    500 µg

    $90

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    1 mg

    $168

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    Product Description

    4-oxo Cyclophosphamide is an inactive metabolite of the alkylating agent cyclophosphamide (Item No. 13849).1,2 It is formed from cyclophosphamide through a 4-hydroxycyclophosphamide intermediate by aldehyde dehydrogenases.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Struck, R.F., Kirk, M.C., Mellett, L.B., et al. Urinary metabolites of the antitumor agent cyclophosphamide. Mol. Pharmacol. 7(5), 519-529 (1971).

    2. de Jonge, M.E., Huitema, A.D.R., Rodenhuis, S., et al. Clinical pharmacokinetics of cyclophosphamide. Clin. Pharmacokinet. 44(11), 1135-1164 (2005).