An inactive metabolite of cyclophosphamide
Related Products
Parent Compound(s)
13849Cyclophosphamide (hydrate)
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Carboxyphosphamide

Item No. 34052

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
3-[[amino[bis(2-chloroethyl)amino]phosphinyl]oxy]-propanoic acid
CAS Number
22788-18-7
Synonyms
  • CPCOOH
  • NSC 145124
Molecular Formula
C7H15Cl2N2O4P
Formula Weight
293.1
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Acetonitrile: SolubleDMSO: SolubleMethanol: Soluble
SMILES
O=C(CCOP(N)(N(CCCl)CCCl)=O)O
InChi Code
InChI=1S/C7H15Cl2N2O4P/c8-2-4-11(5-3-9)16(10,14)15-6-1-7(12)13/h1-6H2,(H2,10,14)(H,12,13)
InChi Key
QLAKAJLYYGOZQL-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    1 mg

    $49

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    5 mg

    $202

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    10 mg

    $376

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    25 mg

    $876

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    Product Description

    Carboxyphosphamide is an inactive metabolite of the alkylating agent cyclophosphamide (Item No. 13849).1 It is formed from cyclophosphamide via oxidation of the intermediate metabolite aldophosphamide by aldehyde dehydrogenase.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Manthey, C.L., and Sladek, N.E. Kinetic characterization of the catalysis of "activated" cyclophosphamide (4-hydroxycyclophosphamide/aldophosphamide) oxidation to carboxyphosphamide by mouse hepatic aldehyde dehydrogenases. Biochem. Pharmacol. 37(14), 2781-2790 (1988).