An internal standard for the quantification of guanine
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Unlabeled Version(s)
34248Guanine
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Guanine-15N5

Item No. 41180

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2-(amino-15N)-1,7-dihydro-6H-purin-6-one-1,3,7,9-15N4
CAS Number
168566-53-8
Molecular Formula
C5H5[15N]5O
Formula Weight
156.1
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Acetonitrile: Slightly soluble: 0.1-1 mg/mlWater: Sparingly soluble: 1-10 mg/ml
SMILES
O=C1[15N]=C([15NH]C2=C1[15NH]C=[15N]2)[15NH2]
InChi Code
InChI=1S/C5H5N5O/c6-5-9-3-2(4(11)10-5)7-1-8-3/h1H,(H4,6,7,8,9,10,11)/i6+1,7+1,8+1,9+1,10+1
InChi Key
UYTPUPDQBNUYGX-CIKZIQIKSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    1 mg

    $160

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    5 mg

    $719

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    Product Description

    Guanine-15N5 is intended for use as an internal standard for the quantification of guanine (Item No. 34248) by GC- or LC-MS. Guanine is a purine base.1 It forms complementary base pairs with the pyrimidine cytosine in DNA and RNA. Guanine can be linked to ribose via a β-N9-glycosidic bond to form the purine nucleoside guanosine (Item No. 27702), which can be phosphorylated to guanine-based purines that have numerous roles in intracellular signal transduction.2,3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Berg, J.M., Tymoczko, J.L., and Stryer, L. Biochemistry. (2002).

    2. Devereaux, Z.J., He, C.C., Zhu, Y., et al. Structures and relative glycosidic bond stabilities of protonated 2'-fluoro-substituted purine nucleosides. J. Am. Soc. Mass Spectrom. 30(8), 1521-1536 (2019).

    3. Di Liberto, V., Mudò, G., Garozzo, R., et al. The guanine-based purinergic system: The tale of an orphan neuromodulation. Front. Pharmacol. 7, 158 (2016).