An oligosaccharide and prebiotic
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Stachyose (hydrate)

Item No. 34322

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
β-D-fructofuranosyl O-α-D-galactopyranosyl-(1→6)-O-α-D-galactopyranosyl-(1→6)-α-D-glucopyranoside, hydrate
CAS Number
54261-98-2
Molecular Formula
C24H42O21 • XH2O
Formula Weight
666.6
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: 1 mg/mlPBS (pH 7.2): 10 mg/ml
SMILES
OC[C@]1(O[C@@H]([C@H]([C@@H]1O)O)CO)O[C@H]2O[C@@H]([C@H]([C@@H]([C@H]2O)O)O)CO[C@H]3O[C@@H]([C@@H]([C@@H]([C@H]3O)O)O)CO[C@H]4O[C@@H]([C@@H]([C@@H]([C@H]4O)O)O)CO.O
InChi Code
InChI=1S/C24H42O21.H2O/c25-1-6-10(28)14(32)17(35)21(41-6)39-3-8-11(29)15(33)18(36)22(42-8)40-4-9-12(30)16(34)19(37)23(43-9)45-24(5-27)20(38)13(31)7(2-26)44-24;/h6-23,25-38H,1-5H2;1H2/t6-,7-,8-,9-,10+,11+,12-,13-,14+,15+,16+,17-,18-,19-,20+,21+,22+,23-,24+;/m1./s1
InChi Key
YDBMRUQRXAFOAH-KTDNCYJLSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    250 mg

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    500 mg

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    1 g

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    5 g

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    Cayman Chemical
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    OBESITY RESEARCH SOLUTIONS
    Product Description

    Stachyose is an oligosaccharide and prebiotic.1,2,3 In vivo, stachyose (1 g/kg per day) reduces the number of colonic lesions and serum TNF-α, IL-6, IL-10, and IL-17a levels, as well as increases gut levels of Akkermansia and the probiotic Lactobacillus, in a rat model of colitis induced by dextran sulfate (DSS; Item No. 23250).1 It decreases serum LPS, IL-6, and TNF-α levels and enriches Phascolarctobacterium, Bilophila, Oscillospira, and Turicibacter in the gut microbiota in a rat model of diabetes induced by high-fat diet and streptozotocin (STZ; Item No. 13104).2 Stachyose also enhances berberine-induced blood glucose control and improvements in insulin resistance, as well as decreases the fecal concentration of short-chain fatty acids, in the KKAγ mouse model of type 2 diabetes.3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. He, L., Zhang, F., Jian, Z., et al. Stachyose modulates gut microbiota and alleviates dextran sulfate sodium-induced acute colitis in mice. Saudi J. Gastroenterol. 26(3), 153-159 (2020).

    2. Liu, G., Bei, J., Liang, L., et al. Stachyose improves inflammation through modulating gut microbiota of high-fat diet/streptozotocin-induced type 2 diabetes in rats. Mol. Nutr. Food Res. 62(6), e1700954 (2018).

    3. Cao, H., Li, C., Lei, L., et al. Stachyose improves the effects of berberine on glucose metabolism by regulating intestinal microbiota and short-chain fatty acids in spontaneous type 2 diabetic KKAy mice. Front. Pharmacol. 11, 578943 (2020).