A pyrethroid acaricide
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τ-Fluvalinate

Item No. 34520

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-[2-chloro-4-(trifluoromethyl)phenyl]-D-valine, cyano(3-phenoxyphenyl)methyl ester
CAS Number
102851-06-9
Synonyms
  • tau-Fluvalinate
Molecular Formula
C26H22ClF3N2O3
Formula Weight
502.9
Purity
≥90%
Formulation (Request formulation change)
A liquid
Solubility(Learn about Variance in Solubility)
DMF: 10 mg/mlDMSO: 10 mg/mlEthanol: 10 mg/ml
λmax
256 nm
SMILES
FC(F)(F)C1=CC(Cl)=C(N[C@H](C(C)C)C(OC(C2=CC=CC(OC3=CC=CC=C3)=C2)C#N)=O)C=C1
InChi Code
InChI=1S/C26H22ClF3N2O3/c1-16(2)24(32-22-12-11-18(14-21(22)27)26(28,29)30)25(33)35-23(15-31)17-7-6-10-20(13-17)34-19-8-4-3-5-9-19/h3-14,16,23-24,32H,1-2H3/t23?,24-/m1/s1
InChi Key
INISTDXBRIBGOC-XMMISQBUSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    τ-Fluvalinate is a pyrethroid acaricide.1 It induces tail currents in Western honeybee (A. mellifera) voltage-gated sodium channels (AmNav1) expressed in Xenopus oocytes (EC50 = 60 nM). It also induces tail currents in honeybee parasitic Varroa mite (V. destructor) Nav1 channels (VdNav1) expressed in Xenopus oocytes (EC50 = 160 nM) with a faster tail current decay than that of AmNav1 channels. Topical application of τ-fluvalinate (2 µl) in combination with coumaphos (Item No. 24230), atrazine (Item No. 13375), 2,4-DMPF, chlorpyrifos (Item No. 21412), and chlorothalonil (Item No. 24142) does not affect honeybee queen mass, egg-laying patterns, or the mass of daughter worker bees at emergence.2 Formulations containing τ-fluvalinate have been used to control Varroa mites in beehives.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Gosselin-Badaroudine, P., and Chahine, M. Biophysical characterization of the Varroa destructor NaV1 sodium channel and its affinity for τ-fluvalinate insecticide. FASEB J. 31(7), 3066-3071 (2017).

    2. McAfee, A. Honey bee queen health is unaffected by contact exposure to pesticides commonly found in beeswax. Sci. Rep. 11(1), 15151 (2021).