A carcinogen
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N-Nitroso Sarcosine

Item No. 34734

Technical Information
Formal Name
2-(methylnitrosoamino)-acetic acid
CAS Number
13256-22-9
Synonyms
  • MCMN
  • N-Methyl-N-(carboxymethyl)nitrosamine
Molecular Formula
C3H6N2O3
Formula Weight
Purity
≥95%
A solid
DMF: 15 mg/mlDMSO: 10 mg/mlEthanol: 30 mg/mlPBS (pH 7.2): 5 mg/ml
SMILES
O=NN(CC(O)=O)C
InChi Code
InChI=1S/C3H6N2O3/c1-5(4-8)2-3(6)7/h2H2,1H3,(H,6,7)
InChi Key
HJMPSKKJHVWPBK-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    Product Description

    N-Nitroso sarcosine is a carcinogen and nitrosation product of sarcosine (Item No. 26799) that has been found in cured meat products.1,2 In vivo, N-nitroso sarcosine (225 mg/kg) induces the formation of metastatic liver carcinomas in mice.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Janzowski, C., Eisenbrand, G., and Preussmann, R. Occurrence of N-nitrosamino acids in cured meat products and their efffect on formation of N-nitrosamines during heating. Food Cosmet. Toxicol. 16(4), 343-348 (1978).

    2. Wogan, G.N., Paglialunga, S., Archer, M.C., et alCarcinogenicity of nitrosation products of ephedrine, sarcosine, folic acid, and creatinine. Cancer Res. 35(8), 1981-1984 (1975).