A metabolite of lithocholic acid
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6-keto Lithocholic Acid

Item No. 35373

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(3α,5β)-3-hydroxy-6-oxo-cholan-24-oic acid
CAS Number
2393-61-5
Synonyms
  • 5β-Cholanic Acid-3α-ol-6-one
  • 6-KLCA
  • 6-keto LCA
  • 6-oxo LCA
  • 6-oxo Lithocholic Acid
  • 6-keto Lithocholate
  • 6-oxo Lithocholate
Molecular Formula
C24H38O4
Formula Weight
390.6
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Dichloromethane: Slightly SolubleDMSO: Slightly SolubleMethanol: Slightly Soluble
SMILES
C[C@H](CCC(O)=O)[C@@]1([H])CC[C@@]2([H])[C@]3([H])CC([C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@@]21C)=O
InChi Code
InChI=1S/C24H38O4/c1-14(4-7-22(27)28)17-5-6-18-16-13-21(26)20-12-15(25)8-10-24(20,3)19(16)9-11-23(17,18)2/h14-20,25H,4-13H2,1-3H3,(H,27,28)/t14-,15-,16+,17-,18+,19+,20+,23-,24-/m1/s1
InChi Key
JWZBXKZZDYMDCJ-IJPFKRJSSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    10 mg

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    25 mg

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    50 mg

    $174

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    100 mg

    $251

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    Cayman Chemical
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    Product Description

    6-keto Lithocholic acid is a metabolite of the secondary bile acid lithocholic acid (Item No. 20253).1 It is formed from lithocholic acid by the cytochrome P450 (CYP) isoforms CYP3A1 and CYP3A2.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Deo, A.K., and Bandiera, S.M. Biotransformation of lithocholic acid by rat hepatic microsomes: Metabolite analysis by liquid chromatography/mass spectrometry. Drug Metab. Dispos. 36(2), 442-451 (2008).