An N-nitrosamine
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N-Nitroso-N-methylaniline

Item No. 35563

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-methyl-N-nitroso-benzenamine
CAS Number
614-00-6
Synonyms
  • N-methyl-N-Nitrosoaniline
  • NMA
  • NSC 137
Molecular Formula
C7H8N2O
Formula Weight
136.2
Purity
≥98%
Formulation (Request formulation change)
A 50 mg/ml solution in ethanol
Solubility(Learn about Variance in Solubility)
Chloroform: SolubleDMSO: SolubleEthanol: SolubleMethanol: Soluble
λmax
272 nm
SMILES
O=NN(C)C1=CC=CC=C1
InChi Code
InChI=1S/C7H8N2O/c1-9(8-10)7-5-3-2-4-6-7/h2-6H,1H3
InChi Key
MAXCWSIJKVASQC-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    25 mg

    $96

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    50 mg

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    100 mg

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    250 mg

    $666

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    Cayman Chemical
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    Product Description

    N-Nitroso-N-methylaniline is an N-nitrosamine.1 It induces the formation of esophageal, pharyngeal, and tongue tumors in rats when administered at a concentration of 200 mg/L in the drinking water or 15 mg/ml via oral gavage.2 N-Nitroso-N-methylaniline is toxic to rats with LD50 values of 336 and 225 mg/kg for male and female rats, respectively. It reduces survival of hamsters but only induces a low incidence of tumors in this species when administered at a dose of 5 mg/week for a total dose of 1.8 mmol.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Lijinsky, W., and Kovatch, R.M. Comparative carcinogenesis by nitrosomethylalkylamines in Syrian hamsters. Cancer Res. 48(23), 6648-6652 (1988).

    2. Goodall, C.M., Lijinsky, W., Tomatis, L., et al. Toxicity and oncogenicity of nitrosomethylaniline and nitrosomethylcyclohexylamine. Toxicol. Appl. Pharmacol. 17(2), 426-432 (1970).