An Analytical Reference Standard
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Isomer(s)
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Metabolite(s)
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Fluorphine

Item No. 36302

Product Insert (PDF)Technical Brief (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
1-[1-[1-(4-fluorophenyl)ethyl]-4-piperidinyl]-1,3-dihydro-2H-benzimidazol-2-one
CAS Number
6440-42-2
Molecular Formula
C20H22FN3O
Formula Weight
339.4
Purity
≥98%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMSO: 1 mg/mlEthanol: Slightly soluble
SMILES
CC(C1=CC=C(F)C=C1)N2CCC(N3C(NC4=C3C=CC=C4)=O)CC2
InChi Code
InChI=1S/C20H22FN3O/c1-14(15-6-8-16(21)9-7-15)23-12-10-17(11-13-23)24-19-5-3-2-4-18(19)22-20(24)25/h2-9,14,17H,10-13H2,1H3,(H,22,25)
InChi Key
ZIGVSUYDKUDHPY-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

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    Product Description

    Fluorphine (Item No. 36302) is an analytical reference standard categorized as an opioid.1,2 Fluorphine induces respiratory depression in mice.2 This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Kennedy, N.M., Schmid, C.L., Ross, N.C., et al. Optimization of a series of mu opioid receptor (MOR) agonists with high G protein signaling bias. J. Med. Chem. 61(19), 8895-8907 (2018).

    2. Vandeputte, M.M., Bilel, S., Tirri, M., et al. Elucidating the harm potential of brorphine analogues as new synthetic opioids: Synthesis, in vitro, and in vivo characterization. Neuropharmacology 260, 110113 (2024).

    Product Citations

    Lenzi, M., Gasperini, S., Bilel, S., et al. New synthetic opioids: What do we know about the mutagenicity of brorphine and its analogues? Int. J. Mol. Sci. 26(11), 5084 (2025).