A derivative of glycine
Related Products
Isomer(s)
167253-Guanidinopropionic Acid
Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

Creatine (hydrate)

Item No. 36940

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-(aminoiminomethyl)-N-methyl-glycine, monohydrate
CAS Number
6020-87-7
Molecular Formula
C4H9N3O2 • H2O
Formula Weight
149.1
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: 1 mg/mlPBS (pH 7.2): 5 mg/ml
SMILES
O=C(CN(C)C(N)=N)O.O
InChi Code
InChI=1S/C4H9N3O2.H2O/c1-7(4(5)6)2-3(8)9;/h2H2,1H3,(H3,5,6)(H,8,9);1H2
InChi Key
MEJYXFHCRXAUIL-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    50 g

    $29

    Add

    100 g

    $46

    Add

    250 g

    $99

    Add

    500 g

    $169

    Add
    Product Description

    Creatine is a derivative of the amino acid glycine.1 It is produced from glycine and L-arginine by arginine:glycine amidinotransferase (AGAT) and guanidinoacetate N-methyltransferase (GAMT) via a guanidinoacetate intermediate. Creatine circulates in the blood and enters tissues via the creatine transporter. In tissues, it is phosphorylated to creatine phosphate (Item Nos. 35598 | 37803), which is used as a reservoir of phosphoryl groups that can be transferred to ATP for the first few seconds of energy consumption, particularly in high-energy consumption tissues such as the brain and skeletal muscle.2 Decreased brain levels of creatine are associated with inborn errors of creatine metabolism characterized by deficiency of AGAT, GAMT, or the creatine transporter.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Item, C.B., Stöckler-Ipsiroglu, S., Stromberger, C., et al. Arginine:Glycine amidinotransferase deficiency: The third inborn error of creatine metabolism in humans. Am. J. Hum. Genet. 69(5), 1127-1133 (2001).

    2. Berg, J.M., Tymoczko, J.L., and Stryer, L. Metabolism: Basic concepts and design. Biochemistry (2002).