An oxylipin gut microbiota metabolite
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10-oxo-12(Z),15(Z)-Octadecadienoic Acid

Item No. 36976

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
10-oxo-12Z,15Z-octadecadienoic acid
CAS Number
1036406-73-1
Synonyms
  • 10-oxo-12(Z),15(Z)-18:2
  • 10-oxo-12(Z),15(Z)-ODE
Molecular Formula
C18H30O3
Formula Weight
294.4
Purity
≥98%
Formulation (Request formulation change)
A 100 µg/ml solution in ethanol
Solubility(Learn about Variance in Solubility)
Ethanol: 1 mg/ml
SMILES
CC/C=C\C/C=C\CC(CCCCCCCCC(O)=O)=O
InChi Code
InChI=1S/C18H30O3/c1-2-3-4-5-8-11-14-17(19)15-12-9-6-7-10-13-16-18(20)21/h3-4,8,11H,2,5-7,9-10,12-16H2,1H3,(H,20,21)/b4-3-,11-8-
InChi Key
HIAXPMGDNFNROF-MLQKXRJWSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    25 µg

    $103

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    50 µg

    $194

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    100 µg

    $366

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    Product Description

    10-oxo-12(Z),15(Z)-Octadecadienoic acid is an oxylipin. It is produced from α-linolenic acid (Item Nos. 90210 | 21910) by the gut bacteria L. plantarum.1 Octadecadienoic acid reduces the increase in mRNA expression levels of the gene encoding SREBP-1c induced by the liver X receptor agonist T0901317 (Item No. 71810) in HepG2 cells.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Nanthirudjanar, T., Furumoto, H., Zheng, J., et al. Gut microbial fatty acid metabolites reduce triacylglycerol levels in hepatocytes. Lipids 50(11), 1093-1102 (2015).