A secondary metabolite
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Isomer(s)
36079Ethopabate
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Lactoyl Phenylalanine

Item No. 37304

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-[(2S)-2-hydroxy-1-oxopropyl]-L-phenylalanine
CAS Number
183241-73-8
Synonyms
  • Lac-Phe
  • N-Lactoyl-Phenylalanine
Molecular Formula
C12H15NO4
Formula Weight
237.3
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMF: 25 mg/mLDMSO: 14 mg/mLEthanol: 20 mg/mLPBS (pH 7.2): 0.30 mg/mL
SMILES
C[C@H](O)C(N[C@H](C(O)=O)CC1=CC=CC=C1)=O
InChi Code
InChI=1S/C12H15NO4/c1-8(14)11(15)13-10(12(16)17)7-9-5-3-2-4-6-9/h2-6,8,10,14H,7H2,1H3,(H,13,15)(H,16,17)/t8-,10-/m0/s1
InChi Key
IIRJJZHHNGABMQ-WPRPVWTQSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    5 mg

    $124

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    10 mg

    $234

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    25 mg

    $552

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    50 mg

    $919

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    Cayman Chemical
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    OBESITY RESEARCH SOLUTIONS
    Product Description

    Lactoyl phenylalanine is a secondary metabolite.1 It is formed from lactate and phenylalanine by cytosolic non-specific dipeptidase (CNDP2). Lactoyl phenylalanine (50 mg/kg per day) decreases food intake, body weight, and adiposity, as well as improves glucose homeostasis in a mouse model of high-fat diet-induced obesity. Plasma levels of lactoyl phenylalanine are increased following exercise in mice.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Li, V.L., He, Y., Contrepois, K., et al. An exercise-inducible metabolite that suppresses feeding and obesity. Nature 606, 785-790 (2022).