A metabolite of chenodeoxycholic acid
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7α-hydroxy-3-oxo-5β-Cholan-24-oic Acid

Item No. 38159

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(5β)-7α-hydroxy-3-oxo-cholan-24-oic acid
CAS Number
4185-00-6
Synonyms
  • 3-keto-7α-hydroxy-5β-Cholanic Acid
  • 3-Oxochenodeoxycholic Acid
Molecular Formula
C24H38O4
Formula Weight
390.6
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMF: 10 mg/mlDMSO: 10 mg/mlEthanol: 10 mg/mlMethanol: 10/mg/ml
λmax
279 nm
SMILES
C[C@H](CCC(O)=O)[C@@]1([H])CC[C@@]2([H])[C@]3([H])[C@H](O)C[C@]4([H])CC(CC[C@]4(C)[C@@]3([H])CC[C@@]21C)=O
InChi Code
InChI=1S/C24H38O4/c1-14(4-7-21(27)28)17-5-6-18-22-19(9-11-24(17,18)3)23(2)10-8-16(25)12-15(23)13-20(22)26/h14-15,17-20,22,26H,4-13H2,1-3H3,(H,27,28)/t14-,15+,17-,18+,19+,20-,22+,23+,24-/m1/s1
InChi Key
KNVADAPHVNKTEP-CIGXQKLNSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    5 mg

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    10 mg

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    25 mg

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    50 mg

    $526

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    Product Description

    7α-hydroxy-3-oxo-5β-Cholan-24-oic acid is a metabolite of chenodeoxycholic acid (Item Nos. 35346 | 10011286).1 It is formed from chenodeoxycholic acid primarily by the cytochrome P450 (CYP) isoform CYP3A4 but also by CYP3A5 and other P450 enzymes at lower rates.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Deo, A.K., and Bandiera, S.M. Identification of human hepatic cytochrome p450 enzymes involved in the biotransformation of cholic and chenodeoxycholic acid. Drug Metab. Dispos. 36(10), 1983-1991 (2008).