An alkylated ADP derivative
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N6-[(6-Aminohexyl)carbamoylmethyl]-ADP

Item No. 38402

Technical Information
Formal Name
N-[2-[(6-aminohexyl)amino]-2-oxoethyl]-adenosine 5′-(trihydrogen diphosphate)
CAS Number
100826-95-7
Synonyms
  • ACM-Adenosine 5'-diphosphate
  • ACM-ADP
  • N6-[(6-Aminohexyl)carbamoylmethyl]-Adenosine 5'-diphosphate
Molecular Formula
C18H31N7O11P2
Formula Weight
Purity
≥70%
A crystalline solid
PBS (pH 7.2): 10 mg/ml
SMILES
O[C@H]([C@@H]1O)[C@H](N2C=NC3=C(NCC(NCCCCCCN)=O)N=CN=C32)O[C@@H]1COP(O)(OP(O)(O)=O)=O
InChi Code
InChI=1S/C18H31N7O11P2/c19-5-3-1-2-4-6-20-12(26)7-21-16-13-17(23-9-22-16)25(10-24-13)18-15(28)14(27)11(35-18)8-34-38(32,33)36-37(29,30)31/h9-11,14-15,18,27-28H,1-8,19H2,(H,20,26)(H,32,33)(H,21,22,23)(H2,29,30,31)/t11-,14-,15-,18-/m1/s1
InChi Key
MMSIXCSIWMOXLY-XKLVTHTNSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    Product Description

    N6-[(6-Aminohexyl)carbamoylmethyl]-ADP is an alkylated derivative of the nucleotide and ATP precursor ADP (Item Nos. 16778 | 21121).1 N6-[(6-Aminohexyl)carbamoyl-methyl]-ADP, bound to agarose beads, can be phosphorylated via acetate kinase to ATP (Item No. 14498). It has been biotinylated and conjugated to an azidonitrobenzoyl group for use as a photoaffinity probe to visualize the ATPase site of rabbit myosin.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Lindberg, M., and Mosbach, K. Preparation of analogues of ATP, ADP and AMP suitable for binding to matrices and the enzymic interconversion of ATP and ADP in solid phase. Eur. J. Biochem. 53(2), 481-486 (1975).

    2. Sutoh, K., Yamamoto, K., and Wakabayashi, T. Electron microscopic visualization of the ATPase site of myosin by photoaffinity labeling with a biotinylated photoreactive ADP analog. Proc. Natl. Acad. Sci. USA 83(2), 212-216 (1986).