A potential impurity found in commercial preparations of tetrazole-containing sartans
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5-(4'-(Azidomethyl)(1,1'-biphenyl)-2-yl)-2H-tetrazole

Item No. 38780

Technical Information
CAS Number
152708-24-2
Synonyms
  • AZTT
Molecular Formula
C14H11N7
Formula Weight
Purity
≥95%
A solid
DMSO: SolubleMethanol: Soluble
SMILES
[N-]=[N+]=NCC1=CC=C(C2=C(C3=NN=NN3)C=CC=C2)C=C1
InChi Code
InChI=1S/C14H11N7/c15-19-16-9-10-5-7-11(8-6-10)12-3-1-2-4-13(12)14-17-20-21-18-14/h1-8H,9H2,(H,17,18,20,21)
InChi Key
HIWODOJPZXUTRT-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    5-(4'-(Azidomethyl)(1,1'-biphenyl)-2-yl)-2H-tetrazole (AZTT) is a potential impurity found in commercial preparations of tetrazole-containing sartans, including losartan, irbesartan, and valsartan.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Wichitnithad, W., Nantaphol, S., Thitikornpong, W., et alDevelopment and validation of an LC-MS/MS method for simultaneous determination of three organic azido impurities in tetrazole-containing sartans. Arab. J. Chem. 16(8), 104951 (2023).