A biotinylated and PEGylated form of cholesterol
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Cholesterol-PEG(2000)-Biotin

Item No. 39036

Technical Information
Formal Name
(3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-((R)-6-methylheptan-2-yl)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl (2-(2-(5-((3aR,4R,6aS)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)ethoxy)ethyl)carbamate
Synonyms
  • Biotin-PEG2000-Cholesterol
Molecular Formula
(C2H4O)nC40H66N4O4S
Purity
≥90%
A solid
Methanol: Soluble
SMILES
C[C@H](CCCC(C)C)[C@@]1([H])CC[C@@]2([H])[C@]3([H])CC=C4C[C@@H](OC(NCCOCCNC(CCCC[C@H]5SC[C@](N6)([H])[C@@]5([H])NC6=O)=O)=O)CC[C@]4(C)[C@@]3([H])CC[C@@]21C
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    Product Description

    Cholesterol-PEG(2000)-biotin is a biotinylated and PEGylated form of cholesterol (Item Nos. 9003100 | 39088). It has been used as a lipid anchor to immobilize vesicles, liposomes, viral particles, bacteria, or yeast to microfluidic chips.1 As a lipid anchor, cholesterol-PEG(2000)-biotin (10 µM) increases phycoerythrin-conjugated streptavidin density on the surface of mesenchymal stem cells greater than sulfo-NHS-LC-biotin.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Kuhn, P., Eyer, K., Robinson, T., et alA facile protocol for the immobilisation of vesicles, virus particles, bacteria, and yeast cells. Integr. Biol. (Camb). 4(12), 1550-1555 (2012).

    2. Davis, K.A., Peng, H., Chelvarajan, L., et alIncreased yield of gelatin coated therapeutic cells through cholesterol insertion. J. Biomed. Mater Res. A. 109(3), 326-335 (2021).