An internal standard for the quantification of carbaryl
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Unlabeled Version(s)
24139Carbaryl
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Carbaryl-d7

Item No. 39550

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
1-naphthalen-2,3,4,5,6,7,8-d7-ol, 1-(N-methylcarbamate)
CAS Number
362049-56-7
Synonyms
  • Arylam-d7
  • Dyna-carbyl-d7
  • ENT 23969-d7
  • α-Naphthyl methyl Carbamate-d7
  • α-Naphthalenyl methyl Carbamate-d7
  • UC7744-d7
Molecular Formula
C12H4D7NO2
Formula Weight
208.3
Purity
≥99% deuterated forms (d1-d7)
Formulation
A solid
Solubility(Learn about Variance in Solubility)
Chloroform: Slightly solubleEthyl Acetate: Slightly solubleMethanol: Slightly soluble
SMILES
CNC(OC1=C([2H])C([2H])=C([2H])C2=C1C([2H])=C([2H])C([2H])=C2[2H])=O
InChi Code
InChI=1S/C12H11NO2/c1-13-12(14)15-11-8-4-6-9-5-2-3-7-10(9)11/h2-8H,1H3,(H,13,14)/i2D,3D,4D,5D,6D,7D,8D
InChi Key
CVXBEEMKQHEXEN-CFWCETGYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Carbaryl-d7 is intended for use as an internal standard for the quantification of carbaryl (Item No. 24139) by GC- or LC-MS. Carbaryl is a carbamate insecticide.1 It is an inhibitor of acetylcholinesterase (AChE; IC50 = 13.6 nM for the mosquito enzyme). Carbaryl is toxic to fourth instar mosquito larvae (LC50 = 0.83 ppm) and tobacco budworms (LD50 = 0.3 mg/g).2,3 In vivo, carbaryl (30 mg/kg per day) increases the serum levels of IL-4 and IL-10 and decreases serum levels of IL-2, IFN-γ, IL-1β, and TNF-α, spleen and thymus weight, as well as increased lymphocyte proliferation induced by concanavalin A (Item No. 14951), in rats.4 Formulations containing carbaryl have been used to control insects in agriculture.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Zhao, P., Wang, Y., and Jiang, H. Biochemical properties, expression profiles, and tissue localization of orthologous acetylcholinesterase-2 in the mosquito, Anopheles gambiae. Insect. Biochem. Mol. Biol. 43(3), 260-271 (2013).

    2. Suwanchaichinda, C., and Brattsten, L.B. Effects of exposure to pesticides on carbaryl toxicity and cytochrome P450 activities in Aedes albopictus larvae (Diptera: Culicidae). Pestic. Biochem. Physiol. 70(2), 63-73 (2001).

    3. Adkisson, P.L. Development of resistance by the tobacco budworm to endrin and carbaryl. J. Econ. Entomol. 61(1), 37-40 (1968).

    4. Jorsaraei, S.G., Maliji, G., Azadmehr, A., et al. Immunotoxicity effects of carbaryl in vivo and in vitro. Environ. Toxicol. Pharmacol. 38(3), 838-844 (2014).