An internal standard for the quantification of diazinon
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Unlabeled Version(s)
23769Diazinon
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Diazinon-d10

Item No. 39556

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
phosphorothioic acid, O,O-di(ethyl-1,1,2,2,2-d5) O-[6-methyl-2-(1-methylethyl)-4-pyrimidinyl] ester
CAS Number
100155-47-3
Molecular Formula
C12H11D10N2O3PS
Formula Weight
314.4
Purity
≥99% deuterated forms (d1-d10)
Formulation
A 10 mg/ml solution in methanol
Solubility(Learn about Variance in Solubility)
Chloroform: Slightly soluble
SMILES
CC(C)C1=NC(OP(OC([2H])([2H])C([2H])([2H])[2H])(OC([2H])([2H])C([2H])([2H])[2H])=S)=CC(C)=N1
InChi Code
InChI=1S/C12H21N2O3PS/c1-6-15-18(19,16-7-2)17-11-8-10(5)13-12(14-11)9(3)4/h8-9H,6-7H2,1-5H3/i1D3,2D3,6D2,7D2
InChi Key
FHIVAFMUCKRCQO-HXOHQZFQSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

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    Product Description

    Diazinon-d10 is intended for use as an internal standard for the quantification of diazinon (Item No. 23769) by GC- or LC-MS. Diazinon is an insecticide.1 It is lethal to adult and larval beet webworms (LD50s = 0.15 and 464 mg/kg, respectively).2 Diazinon (0.5, 1, and 2 mg/kg) decreases isolated brainstem and forebrain choline acetyltransferase activity, a marker for neurological development, in neonatal rats.3 It is lethal to dogs when administered at doses ranging from 300-500 mg/kg.4 Diazinon (5-50 mg/kg) induces cardiac hemorrhage, increases fatty areas in the pancreas, as well as decreases the thickness of the duodenum and jejunum, in pigs. Formulations containing diazinon have been used in the control of ticks, lice, and flies in agriculture.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Earl, F.L., Melveger, B.E., Reinwall, J.E., et al. Diazinon toxicity-comparative studies in dogs and miniature swine. Toxicol. Appl. Pharmacol. 18(2), 285-295 (1971).

    2. Leonova, I.N., and Slynko, N.M. Life stage variations in insecticidal susceptibility and detoxification capacity of the beet webworm, Pyrausta sticticalis L. (Lep., Pyralidae). J. Appl. Entomol. 128(6), 419-425 (2004).

    3. Slotkin, T.A., Levin, E.D., and Seidler, F.J. Comparative developmental neurotoxicity of organophosphate insecticides: Effects on brain development are separable from systemic toxicity. Environ. Health Perspect. 114(5), 746-751 (2006).

    4. Wang, X.-y., Gao, X.-m., Liu, H., et al. Gene expression profiling of the proliferative effect of periplocin on mouse cardiac microvascular endothelial cells. Chin. J. Integr. Med. 16(1), 33-40 (2010).