An Analytical Reference Standard
Technical Support & Resources

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

N-demethyl Promethazine-d3 (hydrochloride)

Item No. 39871

Product Insert (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • Norpromethazine-d3
  • (±)-N-demethyl Promethazine-d3
  • rac-N-demethyl Promethazine-d3
  • Promethazine EP Impurity C-d3
  • N-desmethyl Promethazine-d3
Technical Information
Formal Name
N-(methyl-d3)-1-(10H-phenothiazin-10-yl)propan-2-amine, monohydrochloride
CAS Number
1330173-19-7
Molecular Formula
C16H15D3N2S • HCl
Formula Weight
309.9
Purity
≥99% deuterated forms (d1-d3)
Formulation
A solid
Solubility(Learn about Variance in Solubility)
DMSO: SolubleMethanol: Soluble
SMILES
CC(NC([2H])([2H])[2H])CN1C2=C(C=CC=C2)SC3=CC=CC=C31.Cl
InChi Code
InChI=1S/C16H18N2S.ClH/c1-12(17-2)11-18-13-7-3-5-9-15(13)19-16-10-6-4-8-14(16)18;/h3-10,12,17H,11H2,1-2H3;1H/i2D3;
InChi Key
DJGGTRGRXVNMMY-MUTAZJQDSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    1 mg

    $164

    Add

    5 mg

    $656

    Add
    Cayman Chemical
    Cayman Spectral Library

    Our free, searchable, GC-MS spectral database contains 70eV EI mass spectral data of 2,000+ of Cayman’s forensic drug standards.

    DOWNLOAD THE DATABASE
    Product Description

    N-demethyl Promethazine-d3 (hydrochloride) (Item No. 39871) is intended for use as an internal standard for the quantification of N-demethyl promethazine by GC- or LC-MS. N-demethyl Promethazine is a phenothiazine metabolite.1 It is a metabolite of promethazine (Item Nos. 21331 | 22450). N-demethyl Promethazine is also a degradation product of promethazine.2 This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Blement, B., and Beckett, A.H. Metabolism of promethazine in vitro. Identificaton of N-oxidized products. Xenobiotica 11(9), 609-618 (1981).

    2. Shearer, C.M., and Beckett, S.M. Promethazine hydrochloride. Analyt. Profiles Drug. Subst. 5, 429-465 (1976).