A Certified Reference Material
Features
  • This product is qualified as a Certified Reference Material (CRM) that has been manufactured and tested to meet ISO/IEC 17025 and ISO 17034 international standards
  • This CRM has been characterized by metrologically valid procedures and may be used as a quantitative analytical reference standard
  • Certificate of analysis provides the certified property values and the associated uncertainties, including a statement of metrological traceability for the certified values
  • Bulk material is available for qualified institutions; please contact our sales department for pricing
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Research Tool(s)
15805(±)-Cotinine-d3
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(±)-Cotinine-d3 (CRM)

A 100 µg/ml and 1 mg/ml solution in methanol

Item No. 40378

Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
1-(methyl-d3)-5-(3-pyridinyl)-2-pyrrolidinone
CAS Number
110952-70-0
Molecular Formula
C10H9D3N2O
Formula Weight
179.2
Formulation
A 100 µg/ml and 1 mg/ml solution in methanol
SMILES
O=C(N1C([2H])([2H])[2H])CCC1C2=CC=CN=C2
InChi Code
InChI=1S/C10H12N2O/c1-12-9(4-5-10(12)13)8-3-2-6-11-7-8/h2-3,6-7,9H,4-5H2,1H3/i1D3
InChi Key
UIKROCXWUNQSPJ-FIBGUPNXSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    100 µg

    $43

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    Product Description

    (±)-Cotinine-d3 (CRM) (Item No. 40378) is intended for use as an internal standard for the quantification of cotinine by GC- or LC-MS. (±)-Cotinine is categorized as an alkaloid.1,2 It is an active metabolite of (+)-nicotine and (–)-nicotine.3 This product is intended for analytical forensic applications. This product is also available as a general research tool (Item No. 15805).

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Nwosu, C.G., Godin, C.S., Houdi, A.A., et al. Enantioselective metabolism during continuous administration of S-(–)- and R-(+)-nicotine isomers to guinea-pigs. J. Pharm. Pharmacol. 40(12), 862-869 (1988).

    2. Nwosu, C.G., and Crooks, P.A. Species variation and stereoselectivity in the metabolism of nicotine enantiomers. Xenobiotica 18(12), 1361-1372 (1988).

    3. Clemens, K.J., Caillé, S., Stinus, L., et al. The addition of five minor tobacco alkaloids increases nicotine-induced hyperactivity, sensitization and intravenous self-administration in rats. Int. J. Neuropsychopharmacol. 12(10), 1355-1366 (2009).