An internal standard for the quantification of cotinine
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Analytical Standard(s)
40378(±)-Cotinine-d3 (CRM)
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(±)-Cotinine-d3

Item No. 15805

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
1-(methyl-d3)-5-(3-pyridinyl)-2-pyrrolidinone
CAS Number
110952-70-0
Molecular Formula
C10H9D3N2O
Formula Weight
179.2
Purity
≥99% deuterated forms (d1-d3)
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMSO: 30 mg/mlEthanol: 30 mg/mlPBS (pH 7.2): 10 mg/ml
SMILES
O=C(N1C([2H])([2H])[2H])CCC1C2=CC=CN=C2
InChi Code
InChI=1S/C10H12N2O/c1-12-9(4-5-10(12)13)8-3-2-6-11-7-8/h2-3,6-7,9H,4-5H2,1H3/i1D3
InChi Key
UIKROCXWUNQSPJ-FIBGUPNXSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    5 mg

    $91

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    10 mg

    $161

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    25 mg

    $357

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    Cayman Chemical
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    Product Description

    (±)-Cotinine-d3 is intended for use as an internal standard for the quantification of cotinine by GC- or LC-MS. Cotinine is an alkaloid found in tobacco and a major metabolite of nicotine (Item No. 16535).1,2 It is formed by oxidation of nicotine by the cytochrome P450 (CYP) isoform CYP2A6.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Stålhandske, T. The metabolism of nicotine and cotinine by a mouse liver preparation. Acta. Physiol. Scand. 78(2), 236-248 (1970).

    2. Murphy, S.E., Link, C.A., Jensen, J., et al. A comparison of urinary biomarkers of tobacco and carcinogen exposure in smokers. Cancer Epidemiol. Biomarkers Prev. 13(10), 1617-1623 (2004).