Related Products
Unlabeled Version(s)
100090276α-hydroxy Paclitaxel
Technical Support & Resources

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

6α-hydroxy Paclitaxel-d5

Item No. 40926

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(αR,βS)-β-(benzoyl-2,3,4,5,6-d5-amino)-α-hydroxy-benzenepropanoic acid, (2aR,3S,4R,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-3,4,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester
CAS Number
1315376-90-9
Synonyms
  • 6α-hydroxy Taxol-d5
Molecular Formula
C47H46D5NO15
Formula Weight
874.9
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMF: SolubleDMSO: SolubleMethanol: Soluble
SMILES
C[C@]1(C([C@@H](C2=C(C)[C@@H](OC([C@H](O)[C@H](C3=CC=CC=C3)NC(C4=C([2H])C([2H])=C([2H])C([2H])=C4[2H])=O)=O)C[C@]5(O)C2(C)C)OC(C)=O)=O)[C@@]([C@@H]5OC(C6=CC=CC=C6)=O)([H])[C@@]([C@@]7([H])[C@@H](O)[C@@H]1O)(CO7)OC(C)=O
InChi Code
InChI=1S/C47H51NO15/c1-24-30(61-43(57)33(51)32(27-16-10-7-11-17-27)48-41(55)28-18-12-8-13-19-28)22-47(58)40(62-42(56)29-20-14-9-15-21-29)36-45(6,38(54)35(60-25(2)49)31(24)44(47,4)5)37(53)34(52)39-46(36,23-59-39)63-26(3)50/h7-21,30,32-37,39-40,51-53,58H,22-23H2,1-6H3,(H,48,55)/t30-,32-,33+,34-,35+,36-,37-,39+,40-,45-,46+,47+/m0/s1/i8D,12D,13D,18D,19D
InChi Key
NDCWHEDPSFRTDA-NZSUPHSRSA-N
Origin
Synthetic
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    1 mg

    $1,759

    Add
    Cayman Chemical
    Visit Our Cancer Resource Center
    Find Tools & Resources to Study the Hallmarks of Cancer
    • Cancer cell signaling & regulation
    • Cancer metabolism
    • Tumor microenvironment
    EXPLORE NOW
    Product Description

    6α-hydroxy Paclitaxel-d5 is intended for use as an internal standard for the quantification of 6α-hydroxy paclitaxel (Item No. 10009027) by GC- or LC-MS. 6α-hydroxy Paclitaxel is a metabolite of the antimitotic and anticancer agent paclitaxel (Item No. 10461).1 It is formed from paclitaxel by the cytochrome P450 (CYP) isoform CYP2C8.1,2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Kumar, G.N., Oatis, J.E., Jr., Thornburg, K.R., et al. 6 alpha-Hydroxytaxol: Isolation and identification of the major metabolite of taxol in human liver microsomes. Drug Metab. Dispos. 22(1), 177-179 (1994).

    2. Walle, T., Kumar, G.N., McMillian, J.M., et al. Taxol metabolism in rat hepatocytes. Biochem. Pharmacol. 46(9), 1661-1664 (1993).