A phytosterol with diverse biological activities
Related Products
Labeled Version(s)
45690Campesterol-d7
Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

Campesterol

Item No. 41695

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(3β,24R)-ergost-5-en-3-ol
CAS Number
474-62-4
Synonyms
  • Campesterin
  • NSC 224330
Molecular Formula
C28H48O
Formula Weight
400.7
Purity
≥98% (mixture of epimers)
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Chloroform: Sparingly soluble: 1-10 mg/mlMethanol: Sparingly soluble: 1-10 mg/ml
SMILES
C[C@@]12[C@](CC[C@]2([H])[C@@H](CC[C@@H](C)C(C)C)C)([H])[C@@]3([H])[C@@](CC1)([H])[C@@]4(C(C[C@H](CC4)O)=CC3)C
InChi Code
InChI=1S/C28H48O/c1-18(2)19(3)7-8-20(4)24-11-12-25-23-10-9-21-17-22(29)13-15-27(21,5)26(23)14-16-28(24,25)6/h9,18-20,22-26,29H,7-8,10-17H2,1-6H3/t19-,20-,22+,23+,24-,25+,26+,27+,28-/m1/s1
InChi Key
SGNBVLSWZMBQTH-PODYLUTMSA-N
Origin
Plant/Soybean
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    1 mg

    $32

    Add

    5 mg

    $104

    Add

    10 mg

    $192

    Add

    25 mg

    $439

    Add
    Kinase Resource Center
    Discover Products & Resources for Kinase Research
    • Kinase inhibitors, screening libraries, assay kits, & more
    • Tools to study kinase signaling pathways:
      • Growth factor signaling
      • PI3K/Akt/mTOR
      • MAPKs (ERK, p38, & JNK)
      • JAK/STAT signaling
    • Articles, resources, & advice
    EXPLORE NOW
    Product Description

    Campesterol is a phytosterol that has been found in D. innoxia and has diverse biological activities.1,2,3,4 It inhibits basic FGF-induced proliferation in, and vessel formation by, human umbilical vein endothelial cells (HUVECs) when used at concentrations of 1, 5, or 10 µM.2 Campesterol (15 µM) decreases the proliferation of MCF-7 and ZR-75-1 breast cancer cells.3 It reduces the levels of estrogen receptor α (ERα) in, and the diameter of, patient-derived breast cancer organoids when used at a concentration of 10 µM. Campesterol has been used as a marker of cholesterol intestinal absorption in humans.4

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Ramadan, M.F., Zayed, R., and El-Shamy, H. Screening of bioactive lipids and radical scavenging potential of some solanaceae plants. Food Chem. 103(3), 885-890 (2007).

    2. Choi, J.M., Lee, E.O., Lee, H.J., et al. Identification of campesterol from Chrysanthemum coronarium L. and its antiangiogenic activities. Phytother. Res. 21(10), 954-959 (2007).

    3. Majumder, R., Banerjee, S., Mandal, M., et al. A virtual drug discovery screening illuminates campesterol as a potent estrogen receptor alpha inhibitor in breast cancer. J. Med. Chem. 67(12), 10321-10335 (2024).

    4. Wu, A.H., Ruan, W., Todd, J., et al. Biological variation of β-sitosterol, campesterol, and lathosterol as cholesterol absorption and synthesis biomarkers. Clin. Chim. Acta 430, 43-47 (2014).