An internal standard for the quantification of glyphosate
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Unlabeled Version(s)
28858Glyphosate
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Glyphosate-d2

Item No. 43145

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-(phosphonomethyl)-glycine-2,2-d2
CAS Number
2734001-36-4
Molecular Formula
C3H6D2NO5P
Formula Weight
171.1
Purity
≥99% deuterated forms (d1-d2)
Formulation
A solid
Solubility(Learn about Variance in Solubility)
DMSO: Slightly solublePBS (pH 7.2): Slightly soluble
SMILES
OC(C([2H])([2H])NCP(O)(O)=O)=O
InChi Code
InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)/i1D2
InChi Key
XDDAORKBJWWYJS-DICFDUPASA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    500 µg

    $70

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    1 mg

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    5 mg

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    Product Description

    Glyphosate-d2 is intended for use as an internal standard for the quantification of glyphosate (Item No. 28858) by GC- or LC-MS. Glyphosate is a broad-spectrum, post-emergence herbicide.1 It inhibits the activity of 5-enolpyruvyl-shikimate-3-phosphate synthase (EPSPS; IC50 = 5-7 µM in a cell-free A. aerogenes extract), an enzyme in the shikimate pathway that catalyzes the conversion of shikimic acid to anthranilic acid.2,3 Foliar application of glyphosate induces foliage and rhizome necrosis of johnsongrass (S. halepense) when applied at concentrations ranging from 0.56 to 2.24 kg/hectare.4 It has been found in soil, surface water, and groundwater samples.3 Formulations containing glyphosate have been used for weed control in agriculture and horticulture.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Araújo, A.S.F., Monteiro, R.T.R., and Abarkeli, R.B. Effect of glyphosate on the microbial activity of two Brazilian soils. Chemosphere 52(5), 799-804 (2003).

    2. Steinrücken, H.C., and Amrhein, N. The herbicide glyphosate is a potent inhibitor of 5-enolpyruvyl-shikimic acid-3-phosphate synthase. Biochem. Biophys. Res. Commun. 94(4), 1207-1212 (1980).

    3. Kanissery, R., Geirhe, B., Kadyampakeni, D., et al. Glyphosate: Its environmental persistence and impact on crop health and nutrition. Plants (Basel) 8(11), 499 (2019).

    4. Parochetti, J.V., Wilson, H.P., and Burt, G.W. Activity of glyphosate on johnsongrass. Weed Sci. 23(5), 395-400 (1975).