A Certified Reference Material
Features
  • This product is qualified as a Certified Reference Material (CRM) that has been manufactured and tested to meet ISO/IEC 17025 and ISO 17034 international standards
  • This CRM has been characterized by metrologically valid procedures and may be used as a quantitative analytical reference standard
  • Certificate of analysis provides the certified property values and the associated uncertainties, including a statement of metrological traceability for the certified values
  • Possession of a DEA Controlled Substance registration is not necessary nor is a DEA 222 form required to purchase this product
  • Bulk material is available for qualified institutions; please contact our sales department for pricing
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Metonitazene (CRM)

A 1 mg/ml solution in methanol

Item No. 43158

Exempt Product (US & Canada)
Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N,N-diethyl-2-[(4-methoxyphenyl)methyl]-5-nitro-1H-benzimidazole-1-ethanamine
CAS Number
14680-51-4
Molecular Formula
C21H26N4O3
Formula Weight
382.5
Formulation
A 1 mg/ml solution in methanol
SMILES
CCN(CC)CCN1C(CC2=CC=C(OC)C=C2)=NC3=CC([N+]([O-])=O)=CC=C31
InChi Code
InChI=1S/C21H26N4O3/c1-4-23(5-2)12-13-24-20-11-8-17(25(26)27)15-19(20)22-21(24)14-16-6-9-18(28-3)10-7-16/h6-11,15H,4-5,12-14H2,1-3H3
InChi Key
HNGZTLMRQTVPBH-UHFFFAOYSA-N
Regulatory Information
DEA Exempt Notification
This product is a DEA exempt preparation of a scheduled compound - does not require DEA Controlled Substance registration or DEA 222 form. For alternate sizes please contact sales.
Canada Exempt Notification
This product is registered as a Canada Test Kit - no additional Health Canada import paperwork or permits required.
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

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    1 mg

    $175

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    Product Description

    Metonitazene (CRM) (Item No. 43158) is a certified reference material categorized as an opioid.1 Metonitazene has analgesic effects in mice.2 Metonitazene is regulated as a Schedule I compound in the United States. Metonitazene (CRM) (Item No. 43158) is provided as a DEA exempt preparation. This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Vandeputte, M.M., Van Uytfanghe, K., Layle, N.K., et al. Synthesis, chemical characterization, and µ-opioid receptor activity assessment of the emerging group of "nitazene" 2-benzylbenzimidazole synthetic opioids. ACS Chem. Neurosci. 12(7), 1241-1251 (2021).

    2. Ujváry, I., Christie, R., Evans-Brown, M., et al. DARK classics in chemical neuroscience: Etonitazene and related benzimidazoles. ACS Chem. Neurosci. 12(7), 1072-1092 (2021).

    Product Citations

    Leonard, A.C., Lenert-Mondou, C., Chayer, R., et al. Computational design of dynamic biosensors for emerging synthetic opioids. BioRxiv (2025).