A peptide-lipid conjugate
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DSPE-PEG(2000)-MACTIDE

Item No. 43956

Product Insert (PDF)
Technical Information
Synonyms
  • 1,2-Distearoyl Phosphatidylethanolamine-PEG(2000)-MACTIDE
  • 1,2-DSPE-PEG(2000)-CD206 Cyclic Peptide Ligand
  • DSPE-PEG(2000)-triazole-F-Ahx-G(CTKSIPPIC)SPGAK
  • DSPE-PEG(2000)-UNO-related Cyclic Peptide
Molecular Formula
(C2H4O)nC140H225N26O32PS2
MW
4,086-5,530 (due to PEG congeners)
Formulation (Request formulation change)
200 µg or 1 mg of DSPE-PEG(2000)-MACTIDE click conjugate
Peptide Sequence
Phe-Ahx-G[CTKSIPPIC]-SPGAK
Storage Buffer
Reconstitute lyophilized conjugate in 0.2 ml ethanol prior to use
Applications
Suitable for LNP formulations
SMILES
O=C(CCC(NCCOCCOCC(NCOP(OCC(OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O)(O)=O)=O)=O)N(CC1=C2C=CC=C1)C3=C(C=CC=C3)C4=C2N(N=N4)C5=CC=C(C[C@H](N)C(NCCCCCC(NCC(N[C@H](C(N[C@H](C(N[C@H](CCCCN)C(N[C@H](C(N[C@H](C(N6CCC[C@H]6C7=O)=O)[C@@H](C)CC)=O)CO)=O)=O)[C@H](O)C)=O)CSSC[C@@H](C(N[C@H](C(N8[C@H](C(NCC(N[C@@H](C)C(N[C@@H](CCCCN)C(N)=O)=O)=O)=O)CCC8)=O)CO)=O)NC([C@H]([C@@H](C)CC)NC([C@H]9N7CCC9)=O)=O)=O)=O)=O)C=C5
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    200 µg

    $220

    Add

    1 mg

    $990

    Add
    Cayman Chemical
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    Product Description

    DSPE-PEG(2000)-MACTIDE is a peptide-lipid conjugate composed of DSPE-PEG(2000)-DBCO conjugated to MACTIDE azide (Item No. 43997), a clickable form of a peptide that binds CD206 on tumor-associated macrophages (TAMs).1 DSPE-PEG(2000)-MACTIDE is intended for use in the targeted delivery of lipid nanoparticles (LNPs) in vitro and in vivo.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Lepland, A., Peranzoni, E., Haljasorg, U., et al. Peptide-drug conjugate for therapeutic reprogramming of tumor-associated macrophages in breast cancer. Adv. Sci. (Weinh) 12(10), e2410288 (2025).