A Certified Reference Material
Features
  • This product is qualified as a Certified Reference Material (CRM) that has been manufactured and tested to meet ISO/IEC 17025 and ISO 17034 international standard
  • This CRM has been characterized by metrologically valid procedures and may be used as a quantitative analytical reference standard
  • Certificate of analysis provides the certified property values and the associated uncertainties, including a statement of metrological traceability for the certified values
  • Bulk material is available for qualified institutions; please contact our sales department for pricing
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(−)-Nicotine (CRM)

A 1 mg/ml solution in methanol

Item No. 44503

Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • (−)-(S)-Nicotine
  • L-Nicotine
Technical Information
Formal Name
3-[(2S)-1-methyl-2-pyrrolidinyl]-pyridine
CAS Number
54-11-5
Molecular Formula
C10H14N2
Formula Weight
162.2
Formulation (Request formulation change)
A 1 mg/ml solution in methanol
SMILES
CN1CCC[C@H]1C2=CC=CN=C2
InChi Code
InChI=1S/C10H14N2/c1-12-7-3-5-10(12)9-4-2-6-11-8-9/h2,4,6,8,10H,3,5,7H2,1H3/t10-/m0/s1
InChi Key
SNICXCGAKADSCV-JTQLQIEISA-N
Shipping & Storage Information
Storage
2°C to 8°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $49

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    Product Description

    Nicotine (CRM) (Item No. 44503) is a certified reference material categorized as an alkaloid and nicotinic acetylcholine receptor (nAChR) agonist.1,2 Nicotine has addictive properties.2,3 This product is intended for analytical forensic applications. This product is also available as a general research tool (Item Nos. 29138 | 20887).

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Clayton, P., Lu, A., and Bishop, L. The pyrolysis of (−)-(S)-nicotine: Racemization and decomposition. Chirality 22(4), 442-446 (2010).

    2. Zaveri, N., Jiang, F., Olsen, C., et al. Novel α3β4 nicotinic acetylcholine receptor-selective ligands. Discovery, structure-activity studies, and pharmacological evaluation. J. Med. Chem. 53(22), 8187-8191 (2010).

    3. Albuquerque, E.X., Pereira, E.F.R., Alkondon, M., et al. Mammalian nicotinic acetylcholine receptors: From structure to function. Physiol. Rev. 89(1), 73-120 (2009).