A Certified Reference Material
Features
  • This product is qualified as a Certified Reference Material (CRM) that has been manufactured and tested to meet ISO/IEC 17025 and ISO 17034 international standards
  • This CRM has been characterized by metrologically valid procedures and may be used as a quantitative analytical reference standard
  • Certificate of analysis provides the certified property values and the associated uncertainties, including a statement of metrological traceability for the certified values
  • Possession of a DEA Controlled Substance registration is not necessary nor is a DEA 222 form required to purchase this product
  • Bulk material is available for qualified institutions; please contact our sales department for pricing
Related Products
Alternative(s)
43236Lormetazepam (CRM)
Analytical Standard(s)
21989Lormetazepam
Parent Compound(s)
15554Diclazepam 28623Diclazepam (CRM)
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Lormetazepam (CRM)

A 1 mg/ml solution in methanol

Item No. 44677

Exempt Product (US)
Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • N-methyl Lorazepam
  • Ro 5-5516
  • Wy 4082
Technical Information
Formal Name
7-chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-1-methyl-2H-1,4-benzodiazepin-2-one
CAS Number
848-75-9
Molecular Formula
C16H12Cl2N2O2
Formula Weight
335.2
Formulation (Request formulation change)
A 1 mg/ml solution in methanol
SMILES
ClC1=CC(C(C2=CC=CC=C2Cl)=NC3O)=C(C=C1)N(C)C3=O
InChi Code
InChI=1S/C16H12Cl2N2O2/c1-20-13-7-6-9(17)8-11(13)14(19-15(21)16(20)22)10-4-2-3-5-12(10)18/h2-8,15,21H,1H3
InChi Key
FJIKWRGCXUCUIG-UHFFFAOYSA-N
Regulatory Information
DEA Exempt Notification
This product is a DEA exempt preparation of a scheduled compound - does not require DEA Controlled Substance registration or DEA 222 form. For alternate sizes please contact sales.
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

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    1 mg

    $26

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    Product Description

    Lormetazepam (CRM) (Item No. 44677) is a certified reference material categorized as a benzodiazepine.1 Lormetazepam is an active metabolite of diclazepam (Item Nos. 28623 | 15554) and is associated with misuse.2,3 Formulations containing lormetazepam have been used in the treatment of insomnia. Lormetazepam is regulated as a Schedule IV compound in the United States. Lormetazepam (CRM) (Item No. 44677) is provided as a DEA exempt preparation. This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Hümpel, M., Illi, V., Milius, W., et al. The pharmacokinetics and biotransformation of the new benzodiazepine lormetazepam in humans. I. Absorption, distribution, elimination and metabolism of lormetazepam-5-14C. Eur. J. Drug Metab. Pharmacokinet. 4(4), 237-243 (1979).

    2. Moosmann, B., Bisel, P., and Auwärter, V. Characterization of the designer benzodiazepine diclazepam and preliminary data on its metabolism and pharmacokinetics. Drug Test Anal. 6(7-8), 757-763 (2014).

    3. Magro, L., Faccini, M., and Leone, R. Lormetazepam addiction. Neuropathology of drug addictions and substance misuse 273-283 (2016).