An aquatic plant growth regulator
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Alternative(s)
17404Endothall
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Endothall (sodium salt)

Item No. 44847

Technical Information
Formal Name
7-oxabicyclo[2.2.1]heptane-2,3-dicarboxylic acid, disodium salt
CAS Number
129-67-9
Molecular Formula
C8H9O5 • 2Na
Formula Weight
Purity
≥95%
A solid
PBS (7.2 pH): Sparingly soluble: 1-10 mg/ml
SMILES
[O-]C(C1C(C(O)=O)C2CCC1O2)=O.[Na+].[Na+]
InChi Code
InChI=1S/C8H10O5.2Na/c9-7(10)5-3-1-2-4(13-3)6(5)8(11)12;;/h3-6H,1-2H2,(H,9,10)(H,11,12);;/q;2*+1/p-1
InChi Key
XRHVZWWRFMCBAZ-UHFFFAOYSA-M
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Endothall is an aquatic plant growth regulator.1 It reduces curly leaf pondweed appearance frequency in and dry biomass from lakes when applied annually at a concentration of 1 mg/L. Endothall reduces leaf chlorophyll content in A. thaliana plants and root length in A. thaliana seedlings (IC50s = 1.36 mM and 13.9 µM, respectively) and decreases duckweed growth rate (IC50 = 10 µM).2 It induces production of ethylene in bean leaves when applied at a concentration of 1 µM.3 Endothall is also an inhibitor of protein phosphatase 2A (PP2A; IC50 = 19-50 nM).4 It is toxic to mice (LD50 = 5-50 mg/kg).

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Johnson, J.A., Jones, A.R., and Newman, R.M. Evaluation of lakewide, early season herbicide treatments for controlling invasive curlyleaf pondweed (Potamogeton crispus) in Minnesota lakes. Lake Reserv. Manag. 28(4), 346-363 (2012).

    2. Bajsa, J., Pan, Z., Dayan, F.E., et alValidation of serine/threonine protein phosphatase as the herbicide target site of endothall. Pestic. Biochem. Physiol. 102(1), 38-44 (2012).

    3. Abeles, A.L., and Abeles, F.B. Biochemical pathway of stress-induced ethylene. Plant Physiol. 50(4), 496-498 (1972).

    4. Li, Y.-M., and Casida, J.E. Cantharidin-binding protein: Identification as protein phosphatase 2A. Proc. Natl. Acad. Sci. USA 89(24), 11867-11870 (1992).