A Certified Reference Material of taurocholic acid
Features
  • This product is qualified as a Certified Reference Material (CRM) that has been manufactured and tested to meet ISO/IEC 17025 and ISO 17034 international standards
  • This CRM has been characterized by metrologically valid procedures and may be used as a quantitative analytical reference standard
  • Certificate of analysis provides the certified property values and the associated uncertainties, including a statement of metrological traceability for the certified values
  • Bulk material is available for qualified institutions; please contact our sales department for pricing
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Taurocholic Acid (CRM)

Item No. 44868

Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2-[[(3α,5β,7α,12α)-3,7,12-trihydroxy-24-oxocholan-24-yl]amino]-ethanesulfonic acid
CAS Number
81-24-3
Synonyms
  • Ethanesulfonic Acid
  • TCA
Molecular Formula
C26H45NO7S
Formula Weight
515.7
Formulation (Request formulation change)
A 1 mg/ml solution in methanol
SMILES
O[C@@H]1C[C@]2([H])C[C@H](O)CC[C@]2(C)[C@]3([H])[C@]1([H])[C@@](CC[C@]4([H])[C@@H](CCC(NCCS(O)(=O)=O)=O)C)([H])[C@]4(C)[C@@H](O)C3
InChi Code
InChI=1S/C26H45NO7S/c1-15(4-7-23(31)27-10-11-35(32,33)34)18-5-6-19-24-20(14-22(30)26(18,19)3)25(2)9-8-17(28)12-16(25)13-21(24)29/h15-22,24,28-30H,4-14H2,1-3H3,(H,27,31)(H,32,33,34)/t15-,16+,17-,18-,19+,20+,21-,22+,24+,25+,26-/m1/s1
InChi Key
WBWWGRHZICKQGZ-HZAMXZRMSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    1 mg

    $119

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    Product Description

    Taurocholic acid (CRM) (Item No. 44868) is a certified reference material categorized as a conjugated bile acid.1 It is a taurine-conjugated form of the primary bile acid cholic acid. Serum levels of taurocholic acid (TCA) are decreased in patients with Crohn's disease and those with ulcerative colitis with no extraintestinal manifestations but are increased in patients with ulcerative colitis accompanied by hepatobiliary disease.2 This product is intended for use in quantitative analytical research applications. This product is also available as a general research tool (Item No. 16215).

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Lefebvre, P., Cariou, B., Lien, F., et al. Role of bile acids and bile acid receptors in metabolic regulation. Physiol. Rev. 89(1), 147-191 (2009).

    2. Gnewuch, C., Liebisch, G., Langmann, T., et al. Serum bile acid profiling reflects enterohepatic detoxification state and intestinal barrier function in inflammatory bowel disease. World J. Gastroenterol. 15(25), 3134-3141 (2009).