A Certified Reference Material of glycochenodeoxycholic acid
Features
  • This product is qualified as a Certified Reference Material (CRM) that has been manufactured and tested to meet ISO/IEC 17025 and ISO 17034 international standards
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Glycochenodeoxycholic Acid (CRM)

Item No. 44904

Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-[(3α,5β,7α)-3,7-dihydroxy-24-oxocholan-24-yl]-glycine
CAS Number
640-79-9
Synonyms
  • GCDCA
Molecular Formula
C26H43NO5
Formula Weight
449.6
Formulation (Request formulation change)
A 1 mg/ml solution in methanol
SMILES
O[C@@H]1CC[C@@]2(C)[C@@](C[C@@H](O)[C@]3([H])[C@]2([H])CC[C@@]4(C)[C@@]3([H])CC[C@]4([H])[C@H](C)CCC(NCC(O)=O)=O)([H])C1
InChi Code
InChI=1S/C26H43NO5/c1-15(4-7-22(30)27-14-23(31)32)18-5-6-19-24-20(9-11-26(18,19)3)25(2)10-8-17(28)12-16(25)13-21(24)29/h15-21,24,28-29H,4-14H2,1-3H3,(H,27,30)(H,31,32)/t15-,16+,17-,18-,19+,20+,21-,24+,25+,26-/m1/s1
InChi Key
GHCZAUBVMUEKKP-GYPHWSFCSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    1 mg

    $139

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    Product Description

    Glycochenodeoxycholic acid (CRM) (Item No. 44904) is a certified reference material categorized as a conjugated bile acid.1 It is a glycine-conjugated form of the primary bile acid chenodeoxycholic acid (Item Nos. 44867 | 10011286). Serum levels of glycochenodeoxycholic acid are decreased in patients with polycystic ovarian syndrome (PCOS) administered metformin.2 This product is intended for use in quantitative analytical research applications. This product is also available as a general research tool (Item No. 16942).

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Lan, W., Chen, Z., Chen, Y., et al. Glycochenodeoxycholic acid impairs transcription factor E3-dependent autophagy-lysosome machinery by disrupting reactive oxygen species homeostasis in L02 cells. Toxicol. Lett. 331, 11-21 (2020).

    2. Yan, Q., Cai, M., Wang, N., et al. Circulating profiles of the bile acid metabolomics in patients with polycystic ovary syndrome treated with metformin or canagliflozin. Pharmacotherapy 46(2), e70092 (2026).