A PEGylated and TCO-functionalized form of cholesterol
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Cholesterol-PEG(2000)-TCO

Item No. 45802

Technical Information
Formal Name
(E)-cyclooct-4-en-1-yl (2-(2-(((((3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-((R)-6-methylheptan-2-yl)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl)oxy)carbonyl)amino)ethoxy)ethyl)carbamate
Synonyms
  • Cholesterol-Polyethylene Glycol-2000-trans-cyclooctene
Molecular Formula
(C2H4O)nC39H64N2O4
Purity
≥95%
A solid
DMSO: Soluble: ≥ 10 mg/mlEthanol: Soluble: ≥ 10 mg/mlPBS (7.2 pH): Slightly soluble: 0.1-1 mg/ml
SMILES
O=C(NCCOCCNC(O[C@H](CC1=CC[C@@]2([H])[C@]3([H])CC[C@@]([C@@H](CCCC(C)C)C)([H])[C@@]3(C)CC[C@]42[H])CC[C@@]14C)=O)OC5CCC/C=C/CC5
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Cholesterol-PEG(2000)-TCO is a PEGylated form of cholesterol (Item Nos. 9003100 | 39088 | 39448) that contains a trans-cyclooctene (TCO) moiety, which reacts with tetrazine rings and can be used for bioorthogonal ligation of lipid nanoparticles (LNPs).

    WARNING This product is not for human or veterinary use.