A vitamin D intermediate
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25-hydroxy Vitamin D3

Item No. 9000683

Technical Information
Formal Name
4-[(2Z)-2-[(5S)-5-hydroxy-2-methylenecyclohexylidene]ethylidene]octahydro-α,α,ε,7a-tetramethyl-(εR,1R,3aS,4E,7aR)-1H-indene-1-pentanol
CAS Number
19356-17-3
Synonyms
  • 25-hydroxy Cholecalciferol
  • RO 8-8892
  • U 32070E
Molecular Formula
C27H44O2
Formula Weight
Purity
≥98%
Formulation
A crystalline solid
DMF: 20 mg/mlDMSO: 10 mg/mlEthanol: 20 mg/mlEthanol:PBS (pH 7.2)(1:2): 0.3 mg/ml
λmax
213, 265 nm
SMILES
[H][C@]([C@]1(C)CCC/2)(CC[C@]1([H])[C@H](C)CCCC(C)(O)C)C2=C\C=C3C[C@@H](O)CCC\3=C
InChi Code
InChI=1S/C27H44O2/c1-19-10-13-23(28)18-22(19)12-11-21-9-7-17-27(5)24(14-15-25(21)27)20(2)8-6-16-26(3,4)29/h11-12,20,23-25,28-29H,1,6-10,13-18H2,2-5H3/b21-11+,22-12-/t20-,23+,24-,25+,27-/m1/s1
InChi Key
JWUBBDSIWDLEOM-DTOXIADCSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    25-hydroxy Vitamin D3 is an intermediate in the pathway leading to the production of 1,25-dihydroxy vitamin D3, the most receptor-active form of vitamin D. 25-hydroxy Vitamin D3, produced in the liver from vitamin D3, is metabolized in the kidney to 1,25-dihydroxy vitamin D3. Plasma or serum levels of 25-hydroxy vitamin D3 are commonly used as an indicator of an individual’s vitamin D status.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Peterlik, M., Boonen, S., Cross, H.S., et alVitamin D and calcium insufficiency-related chronic diseases: An emerging world-wide public health problem. Int. J. Environ. Res. Public Health 6(10), 2585-2607 (2009).