An antibiotic
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Metronidazole

Item No. 9002409

Technical Information
Formal Name
2-methyl-5-nitro-1H-imidazole-1-ethanol
CAS Number
443-48-1
Synonyms
  • MNZ
  • NSC 50364
  • NSC 69587
Molecular Formula
C6H9N3O3
Formula Weight
Purity
≥98%
A crystalline solid
DMF: 15 mg/mlDMSO: 15 mg/mlEthanol: 5 mg/mlPBS (pH 7.2): 2 mg/ml
λmax
229, 311 nm
SMILES
CC1=NC=C([N+]([O-])=O)N1CCO
InChi Code
InChI=1S/C6H9N3O3/c1-5-7-4-6(9(11)12)8(5)2-3-10/h4,10H,2-3H2,1H3
InChi Key
VAOCPAMSLUNLGC-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Metronidazole is an antibiotic that has activity against anaerobic bacteria and protozoa including T. vaginalis, E. histolytica, G. lamblia, C. difficile, and H. pylori.1 It reduces the growth of E. coli in vitro (MIC = 128 mg/L under anaerobic conditions).2 In vivo, metronidazole reduces viable counts of B. fragilis in a rabbit model of infection. Formulations containing metronidazole have been used in the treatment of various infections including H. pylori and C. difficile.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Samuelson, J. Why metronidazole is active against both bacteria and parasites. Antimicrob. Agents Chemother. 43(7), 1533-1541 (1999).

    2. Rylander, M., Holm, S.E., Brorson, J.-E., et alActivity of metronidazole on Bacteroides fragilis and/or Escherichia coli in vitro and in vivo. J. Antimicrob. Chemother. 7(3), 257-267 (1981).