A plasmalogen
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1-(1(Z)-Hexadecenyl)-2-linoleoyl-sn-glycero-3-Phosphocholine

Item No. 9004681

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(7R,17Z,20Z)-7-[[(1Z)-1-hexadecen-1-yloxy]methyl]-4-hydroxy-N,N,N-trimethyl-9-oxo-3,5,8-trioxa-4-phosphahexacosa-17,20-dien-1-aminium, inner salt, 4-oxide
CAS Number
204983-73-3
Synonyms
  • C16(plasm)-18:2-PC
  • ​1-1(Z)-Hexadecenyl-2-Linoleoyl-sn-glycero-3-PC
  • 1-1(Z)-Hexadecenyl-2-(9Z,12Z)-Octadecadienoyl-sn-glycero-3-Phosphocholine
  • 16:0p/18:2-PC
  • PC(P-16:0/18:2)
  • PlgPC 16:0/18:2
Molecular Formula
C42H80NO7P
Formula Weight
742.1
Purity
≥95%
Formulation (Request formulation change)
A 5 mg/ml solution in ethanol
Solubility(Learn about Variance in Solubility)
Ethanol: Soluble
SMILES
O=P(OCC[N+](C)(C)C)([O-])OC[C@H](OC(CCCCCCC/C=C\C/C=C\CCCCC)=O)CO/C=C\CCCCCCCCCCCCCC
InChi Code
InChI=1S/C42H80NO7P/c1-6-8-10-12-14-16-18-20-22-23-25-27-29-31-33-35-42(44)50-41(40-49-51(45,46)48-38-36-43(3,4)5)39-47-37-34-32-30-28-26-24-21-19-17-15-13-11-9-7-2/h14,16,20,22,34,37,41H,6-13,15,17-19,21,23-33,35-36,38-40H2,1-5H3/b16-14-,22-20-,37-34-/t41-/m1/s1
InChi Key
QLEHHUPUHJPURI-PWYDUFMYSA-N
Side Chain Carbon Sum
34:2
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    500 µg

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    1 mg

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    5 mg

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    Product Description

    1-(1(Z)-Hexadecenyl)-2-linoleoyl-sn-glycero-3-phosphocholine is a plasmalogen that contains 1(Z)-hexadecenoic acid and linoleic acid (Item Nos. 90150 | 90150.1 | 21909) at the sn-1 and sn-2 positions, respectively. It inhibits lead-induced decreases in viability and lead-induced increases in reactive oxygen species (ROS) and oxidized phospholipids in HepG2 hepatocytes.1 Serum levels of 1-(1(Z)-Hexadecenyl)-2-linoleoyl-sn-glycero-3-phosphocholine are decreased in dogs with myxomatous mitral valve disease when fed a diet including medium chain triglycerides, fish oil, carnitine precursors, magnesium, and antioxidants.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Wu, Y., Chen, Z., Darwish, W.S., et al. Choline and ethanolamine plasmalogens prevent lead-induced cytotoxicity and lipid oxidation in HepG2 cells. J. Agric. Food Chem. 67(27), 7716-7725 (2019).

    2. Li, Q., Laflamme, D.P., and Bauer, J.E. Serum untargeted metabolomic changes in response to diet intervention in dogs with preclinical myxomatous mitral valve disease. PLoS One 15(6), e0234404 (2020).