A Certified Reference Material
Features
  • This product is qualified as a Certified Reference Material (CRM) that has been manufactured and tested to meet ISO/IEC 17025 and ISO 17034 international standards
  • This CRM has been characterized by metrologically valid procedures and may be used as a quantitative analytical reference standard
  • Certificate of analysis provides the certified property values and the associated uncertainties, including a statement of metrological traceability for the certified values
  • Bulk material is available for qualified institutions; please contact our sales department for pricing
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Dextromethorphan (CRM)

A 1 mg/ml solution in methanol

Item No. ISO60141

Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • DXM
  • D-Methorphan
Technical Information
Formal Name
(9α,13α,14α)-3-methoxy-17-methyl-morphinan
CAS Number
125-71-3
Molecular Formula
C18H25NO
Formula Weight
271.4
Formulation
A 1 mg/ml solution in methanol
SMILES
CN1[C@@H]2[C@@]3([H])CCCC[C@@]3(CC1)C4=CC(OC)=CC=C4C2
InChi Code
InChI=1S/C18H25NO/c1-19-10-9-18-8-4-3-5-15(18)17(19)11-13-6-7-14(20-2)12-16(13)18/h6-7,12,15,17H,3-5,8-11H2,1-2H3/t15-,17+,18+/m1/s1
InChi Key
MKXZASYAUGDDCJ-NJAFHUGGSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

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    Product Description

    Dextromethorphan (CRM) (Item No. ISO60141) is a certified reference material categorized as an antitussive.1 Dextromethorphan has analgesic and anticonvulsant activities in rodents.2,3 It has been found as an adulterant in 3,4-MDMA and has potential for abuse.4,5 This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Bolser, D.C., Aziz, S.M., DeGennaro, F.C., et al. Antitussive effects of GABAB agonists in the cat and guinea-pig. Br. J. Pharmacol. 110(1), 491-495 (1993).

    2. Chen, Y.W., Chu, K.S., Lin, C.N., et al. Dextromethorphan or dextrorphan have a local anesthetic effect on infiltrative cutaneous analgesia in rats. Anesth. Analg. 104(5), 1251-1255 (2007).

    3. Jamali, H., and Heydari, A. Effect of dextromethorphan/quinidine on pentylenetetrazole- induced clonic and tonic seizure thresholds in mice. Neurosci. Lett. 729, 134988 (2020).

    4. Cole, C., Jones, L., McVeigh, J., et al. CUT: A guide to adulterants, bulking agents and other contaminants found in illicit drugs. (2010).

    5. Chomchai, C., and Manaboriboon, B. Stimulant methamphetamine and dextromethorphan use among Thai adolescents: Implications for health of women and children. J. Med. Toxicol. 8(3), 291-294 (2012).