An Analytical Reference Material
Features
  • This product is qualified as a Reference Material that has been manufactured and tested to meet ISO/IEC 17025 and ISO 17034 international standards
  • This product is intended to be used as an analytical reference standard
  • Bulk material is available for qualified institutions; please contact our sales department for pricing
Technical Support & Resources

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

Dextrorphan (tartrate)

Item No. 15886

Product Insert (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • DXO
  • d-3-hydroxy-N-Methylmorphinan
  • NIH 4591
Technical Information
Formal Name
(9α,13α,14α)-17-methyl-morphinan-3-ol 2R,3R-dihydroxybutanedioate
CAS Number
143-98-6
Molecular Formula
C17H23NO • C4H6O6
Formula Weight
407.5
Purity
≥98%
Formulation
A crystalline solid
λmax
200, 219, 281 nm
SMILES
CN1[C@@H]2[C@@]3([H])CCCC[C@@]3(CC1)C4=CC(O)=CC=C4C2.O[C@H]([C@@H](O)C(O)=O)C(O)=O
InChi Code
InChI=1S/C17H23NO.C4H6O6/c1-18-9-8-17-7-3-2-4-14(17)16(18)10-12-5-6-13(19)11-15(12)17;5-1(3(7)8)2(6)4(9)10/h5-6,11,14,16,19H,2-4,7-10H2,1H3;1-2,5-6H,(H,7,8)(H,9,10)/t14-,16+,17+;/m1./s1
InChi Key
RWTWIZDKEIWLKQ-YPYJQMNVSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    1 mg

    $41

    Add

    5 mg

    $99

    Add
    Cayman Chemical
    Forensic Lab Guide Wall Posters

    Discover our collection of drug identification, naming, and metabolism posters for your lab. We offer all of our posters at no cost to help support the forensic community.

    REQUEST YOURS
    Product Description

    Dextrorphan (tartrate) (Item No. 15886) is an analytical reference material categorized as a morphinan.1 Dextrorphan is an active metabolite of dextromethorphan (Item Nos. ISO60141 | 11157 | 13950).2 It has analgesic activity and induces memory impairments in rats and has anticonvulsant activity and induces hyperlocomotion in mice.1,3,4 Dextrorphan substitutes for phencyclidine (PCP; Item Nos. ISO60194 | 14276) in rhesus monkeys.5 This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Chen, Y.W., Chu, K.S., Lin, C.N., et al. Dextromethorphan or dextrorphan have a local anesthetic effect on infiltrative cutaneous analgesia in rats. Anesth. Analg. 104(5), 1251-1255 (2007).

    2. Shin, E.J., Lee, P.H., Kim, H.J., et al. Neuropsychotoxicity of abused drugs: Potential of dextromethorphan and novel neuroprotective analogs of dextromethorphan with improved safety profiles in terms of abuse and neuroprotective effects. J. Pharmacol. Sci. 106(1), 22-27 (2008).

    3. Dematteis, M., Lallement, G., and Mallaret, M. Dextromethorphan and dextrorphan in rats: Common antitussives - different behavioural profiles. Fundam. Clin. Pharmacol. 12(5), 526-537 (1998).

    4. Cho, Y.-C., Liao, J.-F., Chang, W.-Y., et al. Binding of dimemorfan to sigma-1 receptor and its anticonvulsant and locomotor effects in mice, compared with dextromethorphan and dextrorphan. Brain Res. 821(2), 516-519 (1999).

    5. Nicholson, K.L., Hayes, B.A., and Balster, R.L. Evaluation of the reinforcing properties and phencyclidine-like discriminative stimulus effects of dextromethorphan and dextrorphan in rats and rhesus monkeys. Psychopharmacology (Berl) 146(1), 49-59 (1999).