A phenol with diverse biological activities
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Labeled Version(s)
35132Gallic Acid-d2
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Gallic Acid

Item No. 11846

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
3,4,5-trihydroxy-benzoic acid
CAS Number
149-91-7
Synonyms
  • NSC 20103
  • NSC 674319
  • 3,4,5-Trihydroxybenzoic Acid
Molecular Formula
C7H6O5
Formula Weight
170.1
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 25 mg/mlDMSO: 16 mg/mlEthanol: 16 mg/mlPBS (pH 7.2): 2 mg/ml
λmax
218, 273 nm
SMILES
OC1=C(O)C(O)=CC(C(O)=O)=C1
InChi Code
InChI=1S/C7H6O5/c8-4-1-3(7(11)12)2-5(9)6(4)10/h1-2,8-10H,(H,11,12)
InChi Key
LNTHITQWFMADLM-UHFFFAOYSA-N
Origin
Plant/Terminalia chebula
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    10 g

    $36

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    50 g

    $62

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    100 g

    $86

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    Cayman Chemical
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    Product Description

    Gallic acid is a phenol that has been found in C. sinensis and has diverse biological activities.1,2,3,4 It scavenges DPPH (Item No. 14805) and hydroxyl radicals in cell-free assays (IC50s = 9.4 and 191 µM, respectively).1 Gallic acid (1-100 µM) reverses abscisic acid-induced inhibition of hypocotyl growth in A. caudatus seedlings.2 In vivo, gallic acid (21.8 g/kg) inhibits morpholine- and sodium nitrite-induced adenocarcinoma formation in mice.3 It also inhibits passive cutaneous anaphylaxis in mice when administered at a dose of 50 mg/kg.4

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Cos, P., Hermans, N., Calomme, M., et al. Comparative study of eight well-known polyphenolic antioxidants. J. Pharm. Pharmacol. 55(9), 1291-1297 (2003).

    2. Ray, S.D., Guruprasad, K.N., and Laloraya, M.M. Antagonistic action of phenolic compounds on abscisic acid-induced inhibition of hypocotyl growth. J. Exp. Bot. 31(125), 1651-1656 (1980).

    3. Mirvish, S.S., Cardesa, A., Wallcave, L., et al. Induction of mouse lung adenomas by amines or ureas plus nitrite and by N-nitroso compounds: Effect of ascorbate, gallic acid, thiocyanate, and caffeine. J. Natl. Cancer Inst. 55(3), 633-636 (1975).

    4. Kar, K., Mohanta, P.K., Popli, S.P., et al. Inhibition of passive cutaneous anaphylaxis by compounds of Camellia sinensis. Planta Med. 42(1), 75-78 (1981).